ReviewAnnual review of physical chemistry2013
Biomolecular imaging with coherent nonlinear vibrational microscopy.
Review in Annual review of physical chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Article
- In-operando control of sum-frequency generation in tip-enhanced nanocavities.Light, science & applications · 2025Article
- Molecular Fingerprinting of Mouse Brain Using Ultrabroadband Coherent Anti-Stokes Raman Scattering (CARS) Microspectroscopy Empowered by Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS).Chemical & biomedical imaging · 2024Article
- Surpassing the Diffraction Limit in Label-Free Optical Microscopy.ACS photonics · 2024Review
- Label-Free Assessment of Neuronal Activity Using Raman Micro-Spectroscopy.Molecules (Basel, Switzerland) · 2024Article
- Multimodal Nonlinear Hyperspectral Chemical Imaging Using Line-Scanning Vibrational Sum-Frequency Generation Microscopy.Journal of visualized experiments : JoVE · 2023Article
- Spatial sterol metabolism unveiled by stimulated Raman imaging.Frontiers in chemistry · 2023Article
- Monitoring membranes: The exploration of biological bilayers with second harmonic generation.Chemical physics reviews · 2022Review
- Ultrafast Widefield Mid-Infrared Photothermal Heterodyne Imaging.Analytical chemistry · 2022Article
- Imaging Orientation of a Single Molecular Hierarchical Self-Assembled Sheet: The Combined Power of a Vibrational Sum Frequency Generation Microscopy and Neural Network.The journal of physical chemistry. B · 2022Article
- Non-invasive cell classification using the Paint Raman Express Spectroscopy System (PRESS).Scientific reports · 2021Article
- Broadband stimulated Raman scattering microscopy with wavelength-scanning detection.Journal of Raman spectroscopy : JRS · 2020Article
- Smart-Dust-Nanorice for Enhancement of Endogenous Raman Signal, Contrast in Photoacoustic Imaging, and T2-Shortening in Magnetic Resonance Imaging.Small (Weinheim an der Bergstrasse, Germany) · 2018Article
- Hyperspectral imaging with laser-scanning sum-frequency generation microscopy.Biomedical optics express · 2017Article
- Watching Proteins Wiggle: Mapping Structures with Two-Dimensional Infrared Spectroscopy.Chemical reviews · 2017Review
- Effect of scattering on coherent anti-Stokes Raman scattering (CARS) signals.Optics express · 2017Article
- Development and validation of near-infrared spectroscopy for the prediction of forage quality parameters inPeerJ · 2017Article
- Tracking Bulk and Interfacial Diffusion Using Multiplex Coherent Anti-Stokes Raman Scattering Correlation Spectroscopy.The journal of physical chemistry. B · 2016Article
- In Situ and In Vivo Molecular Analysis by Coherent Raman Scattering Microscopy.Annual review of analytical chemistry (Palo Alto, Calif.) · 2016Article
- Broadband coherent Raman spectroscopy running at 24,000 spectra per second.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Optical imaging with spectroscopic vibrational contrast is a label-free solution for visualizing, identifying, and quantifying a wide range of biomolecular compounds in biological materials. Both linear and nonlinear vibrational microscopy techniques derive their imaging contrast from infrared active or Raman allowed molecular transitions, which provide a rich palette for interrogating chemical and structural details of the sample. Yet nonlinear optical methods, which include both second-order sum-frequency generation (SFG) and third-order coherent Raman scattering (CRS) techniques, offer several improved imaging capabilities over their linear precursors. Nonlinear vibrational microscopy features unprecedented vibrational imaging speeds, provides strategies for higher spatial resolution, and gives access to additional molecular parameters. These advances have turned vibrational microscopy into a premier tool for chemically dissecting live cells and tissues. This review discusses the molecular contrast of SFG and CRS microscopy and highlights several of the advanced imaging capabilities that have impacted biological and biomedical research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.