Evidence map›Paper›PMID 23245398›Full record

ReviewHuman genomics2012

GWIDD: a comprehensive resource for genome-wide structural modeling of protein-protein interactions.

Petras J Kundrotas, Zhengwei Zhu, Ilya A Vakser

Abstract readReview
In one paragraph

Review in Human genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Dockground resource for protein recognition studies.Protein science : a publication of the Protein Society · 2022
    Article
  3. Challenges in protein docking.Current opinion in structural biology · 2020
    Review
  4. Article
  5. Article
  6. Frontiers in pharmacology · 2019
    Review
  7. Review
  8. Challenges in structural approaches to cell modeling.Journal of molecular biology · 2016
    Review
  9. Template-based structure modeling of protein-protein interactions.Current opinion in structural biology · 2014
    Review
  10. Low-resolution structural modeling of protein interactome.Current opinion in structural biology · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Petras J Kundrotas
Zhengwei Zhu
Ilya A Vakser

Funding

Integrated Resource for Protein Recognition StudiesR01GM074255 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI VAKSER, ILYA · 2005 to 2024
$6.2M
NIGMS NIH HHS R01 GM074255
6 · The paper itself

Abstract

Protein-protein interactions are a key component of life processes. The knowledge of the three-dimensional structure of these interactions is important for understanding protein function. Genome-Wide Docking Database (http://gwidd.bioinformatics.ku.edu) offers an extensive source of data for structural studies of protein-protein complexes on genome scale. The current release of the database combines the available experimental data on the structure and characteristics of protein interactions with structural modeling of protein complexes for 771 organisms spanned over the entire universe of life from viruses to humans. The interactions are stored in a relational database with user-friendly interface that includes various search options. The search results can be interactively previewed; the structures, downloaded, along with the interaction characteristics.

Indexed as

Databases, ProteinProtein Structure, TertiaryAnimalsComputational BiologyGenomeHumansInformation Storage and RetrievalProtein BindingProtein Interaction MappingProteinsProteins

Identifiers

PMID23245398
PMCPMC3500202

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.