ReviewAnnual review of clinical psychology2013
Neurotoxic effects of alcohol in adolescence.
Review in Annual review of clinical psychology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
136 citing papers in PubMed, 5 syntheses or guidelines pooled it, 269 citations in OpenAlex.
- Effects of Alcohol on EEG Activity: A Systematic Review Focused on Sex-Related Differences in Youth.Current neuropharmacology · 2025Pooled it
- Eye Tracking Studies Exploring Cognitive and Affective Processes among Alcohol Drinkers: a Systematic Review and Perspectives.Neuropsychology review · 2021Pooled it
- Problematic alcohol use and reduced hippocampal volume: a meta-analytic review.Psychological medicine · 2017Pooled it
- Meta-analysis of DSM alcohol use disorder criteria severities: structural consistency is only 'skin deep'.Psychological medicine · 2016Pooled it
- The effect of alcohol consumption on the adolescent brain: A systematic review of MRI and fMRI studies of alcohol-using youth.NeuroImage. Clinical · 2014Pooled it
- Alcohol-induced performance impairment: a 5-year re-examination study in heavy and light drinkers.Psychopharmacology · 2017Trial
- Adolescent heavy drinkers' amplified brain responses to alcohol cues decrease over one month of abstinence.Addictive behaviors · 2015Trial
- Low-Level Alcohol Consumption in Children 11-12 Years Old Is Linked to Neural Substrates Involved in Reward Processing and Inhibitory Control: Results From a Brain-Wide Association Study.Alcohol, clinical & experimental research · 2026Article
- Behavioral Disinhibition Model of Addiction: A Review and New Findings from the Minnesota Twin Family Study.Behavior genetics · 2026Review
- Neural imbalance between feedback sensitivity and motor inhibition in compulsivity and negative urgency.Translational psychiatry · 2026Article
- The Role of Cold-Inducible RNA-Binding Protein (CIRP) in Neurological Disorders.Brain sciences · 2026Review
- Problematic Alcohol Use Among Adolescents in Germany: Representative Cross-Sectional Study.JMIR public health and surveillance · 2026Article
- Development of the Nervous System During Adolescence.Advances in experimental medicine and biology · 2026Review
- The Impacts of Binge Drinking and Hangover on the Social Brain: An Integrative Narrative Review.Biomedicines · 2025Review
- Neuroprotective effects of Simvastatin against alcohol-induced oxidative stress and neurodegeneration in the Hippocampus of adolescent mice.Metabolic brain disease · 2025Article
- Influence of binge drinking on the resting state functional connectivity of university Students: A follow-up study.Addictive behaviors reports · 2025Article
- Higher alcohol use is associated with subsequent increased risk seeking toward gains: A longitudinal cohort study in young men.Alcohol, clinical & experimental research · 2025Article
- Triple network dynamics and future alcohol consumption in adolescents.Alcohol, clinical & experimental research · 2025Article
- Associative memory in alcohol-related contexts: An fMRI study with young binge drinkers.Journal of psychopharmacology (Oxford, England) · 2024Article
- Blood metabolites, neurocognition and psychiatric disorders: a Mendelian randomization analysis to investigate causal pathways.Translational psychiatry · 2024Article
76 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
This review examines neuroimaging and neurocognitive findings on alcohol-related toxicity in adolescents. Teens who meet criteria for alcohol use disorders, as well as those who engage in subdiagnostic binge drinking behaviors, often show poorer neurocognitive performance, alterations in gray and white matter brain structure, and discrepant functional brain activation patterns when compared to nonusing and demographically matched controls. Abnormalities are also observed in teens with a family history of alcoholism, and such differences in neuromaturation may leave youths at increased risk for the development of an alcohol use disorder or increased substance use severity. More prospective investigations are needed, and future work should focus on disentangling preexisting differences from dose-dependent effects of alcohol on neurodevelopment. Intervention strategies that utilize neuroimaging findings (e.g., identified weaknesses in particular neural substrates and behavioral correlates) may be helpful in both prevention and intervention campaigns for teens both pre- and postinitiation of alcohol use.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.