ArticleImmunity2012
Th1 cell induction in lymph nodes according to a red-blue chemokine map.
Article in Immunity, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Th1 cytokine endotype discriminates and predicts severe complications in COVID-19European cytokine network · 2022Article
- Functional heterogeneity of CD4Seminars in immunopathology · 2021Review
- A novel immunochemotherapy based on targeting of cyclooxygenase and induction of immunogenic cell death.Biomaterials · 2021Article
- M1Journal for immunotherapy of cancer · 2020Article
- Identification of a super-functional Tfh-like subpopulation in murine lupus by pattern perception.eLife · 2020Article
- Memory formation and long-term maintenance of IL-7RαNature communications · 2018Article
- Blood Stage Malaria Disrupts Humoral Immunity to the Pre-erythrocytic Stage Circumsporozoite Protein.Cell reports · 2016Article
- MicroRNA-125b modulates inflammatory chemokine CCL4 expression in immune cells and its reduction causes CCL4 increase with age.Aging cell · 2015Article
- Macrophage heterogeneity in tissues: phenotypic diversity and functions.Immunological reviews · 2014Review
- Priming of T follicular helper cells by dendritic cells.Immunology and cell biology · 2014Review
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
Abstract
Lymph nodes are compartmentalized organs but whether this feature has a role in T cell differentiation has been unclear. In this issue, Groom et al. (2012) reveal that spatially separated expression of two CXCR3 ligands guides Th1 cell development.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.