Evidence map›Paper›PMID 23244575›Full record

ArticleHuman genomics2012

Patterns of gene expression in microarrays and expressed sequence tags from normal and cataractous lenses.

Konstantinos Sousounis, Panagiotis A Tsonis

Abstract read
In one paragraph

Article in Human genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Ameliorative effects of SkQ1 eye drops on cataractogenesis in senescence-accelerated OXYS rats.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Konstantinos SousounisDepartment of Biology and Center for Tissue Regeneration and Engineering, University of Dayton, Dayton, OH 45469-2320, USA.
Panagiotis A Tsonis

Funding

Gene Discovery in Mouse Models for Secondary CataractsR01EY016707 · NEI · UNIVERSITY OF DAYTON · PI TSONIS, PANAGIOTIS A · 2007 to 2011
$1.7M
NEI NIH HHS EY16707
6 · The paper itself

Abstract

In this contribution, we have examined the patterns of gene expression in normal and cataractous lenses as presented in five different papers using microarrays and expressed sequence tags. The purpose was to evaluate unique and common patterns of gene expression during development, aging and cataracts.

Indexed as

Gene Expression RegulationOligonucleotide Array Sequence AnalysisAgingAnimalsCataractCluster AnalysisExpressed Sequence TagsGene Expression ProfilingGenetic Association StudiesHumansImmunityLens, CrystallineMiceOsteonectinRNA, MessengerRNA SplicingOsteonectinRNA, Messenger

Identifiers

PMID23244575
PMCPMC3563465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.