ArticleBiomedical optics express2012
A diffuse reflectance spectral imaging system for tumor margin assessment using custom annular photodiode arrays.
Article in Biomedical optics express, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Optical Tissue Phantoms for Quantitative Evaluation of Surgical Imaging Devices.Advanced photonics research · 2023Article
- Discriminating healthy from tumor tissue in breast lumpectomy specimens using deep learning-based hyperspectral imaging.Biomedical optics express · 2022Article
- Quantum Blue Reduces the Severity of Woody Breast Myopathy via Modulation of Oxygen Homeostasis-Related Genes in Broiler Chickens.Frontiers in physiology · 2019Article
- Flexible silicon sensors for diffuse reflectance spectroscopy of tissue.Biomedical optics express · 2017Article
- Miniature spectral imaging device for wide-field quantitative functional imaging of the morphological landscape of breast tumor margins.Journal of biomedical optics · 2017Article
- High responsivity, low dark current, heterogeneously integrated thin film Si photodetectors on rigid and flexible substrates.Optics express · 2014Article
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- A diffuse reflectance spectral imaging system for tumor margin assessment using custom annular photodiode arrays.Biomedical optics express · 2012Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Diffuse reflectance spectroscopy (DRS) is a well-established method to quantitatively distinguish between benign and cancerous tissue for tumor margin assessment. Current multipixel DRS margin assessment tools are bulky fiber-based probes that have limited scalability. Reported herein is a new approach to multipixel DRS probe design, which utilizes direct detection of the DRS signal by using optimized custom photodetectors in direct contact with the tissue. This first fiberless DRS imaging system for tumor margin assessment consists of a 4 × 4 array of annular silicon photodetectors and a constrained free-space light delivery tube optimized to deliver light across a 256 mm(2) imaging area. This system has 4.5 mm spatial resolution. The signal-to-noise ratio measured for normal and malignant breast tissue-mimicking phantoms was 35 dB to 45 dB for λ = 470 nm to 600 nm.
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Registered trials
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