Evidence map›Paper›PMID 23243566›Full record

ArticleBiomedical optics express2012

A liquid optical phantom with tissue-like heterogeneities for confocal microscopy.

Danni Wang, Ye Chen, Jonathan T C Liu

Abstract read
In one paragraph

Article in Biomedical optics express, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Danni WangStony Brook University (SUNY), Department of Biomedical Engineering, Stony Brook, NY 11794, USA.
Ye Chen
Jonathan T C Liu

Funding

Line-scanned MEMS-based dual-axis confocal microscopy to detect oral lesions in vR01DE023497 · NIDCR · UNIVERSITY OF WASHINGTON · PI LIU, JONATHAN T.C. · 2012 to 2014
$2.4M
Dual-axis Confocal Microscope for Image-guided Resection of MedulloblastomaR00EB008557 · NIBIB · STATE UNIVERSITY NEW YORK STONY BROOK · PI LIU, JONATHAN T.C. · 2010 to 2012
$724k
NIBIB NIH HHS R00 EB008557NIDCR NIH HHS R01 DE023497
6 · The paper itself

Abstract

Phantoms play an important role in the development, standardization, and calibration of biomedical imaging devices in laboratory and clinical settings, serving as standards to assess the performance of such devices. Here we present the design of a liquid optical phantom to facilitate the assessment of optical-sectioning microscopes that are being developed to enable point-of-care pathology. This phantom, composed of silica microbeads in an Intralipid base, is specifically designed to characterize a reflectance-based dual-axis confocal (DAC) microscope for skin imaging. The phantom mimics the scattering properties of normal human epithelial tissue in terms of an effective scattering coefficient and a depth-dependent degradation in spatial resolution due to beam steering caused by tissue micro-architectural heterogeneities.

Indexed as

(170.1790) Confocal microscopy(170.3880) Medical and biological imaging(170.5810) Scanning microscopy(170.6900) Three-dimensional microscopy(170.7050) Turbid media

Identifiers

PMID23243566
PMCPMC3521309

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.