Evidence map›Paper›PMID 23243505›Full record

ArticleAutism research and treatment2012

A review of complementary and alternative treatments for autism spectrum disorders.

Nicholas Lofthouse, Robert Hendren, Elizabeth Hurt, L Eugene Arnold, Eric Butter

Abstract read
In one paragraph

Article in Autism research and treatment, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. A Conceptual Framework for Understanding the Cultural and Contextual Factors on Autism Across the Globe.Autism research : official journal of the International Society for Autism Research · 2020
    Pooled it
  2. Pooled it
  3. Trial
  4. Internet-based, randomized, controlled trial of omega-3 fatty acids for hyperactivity in autism.Journal of the American Academy of Child and Adolescent Psychiatry · 2014
    Trial
  5. Review
  6. Review
  7. De-implementation of Low-Value Practices for Autism Spectrum Disorder.Clinical child and family psychology review · 2023
    Review
  8. Practitioner's review: medication for children and adolescents with autism spectrum disorder (ASD) and comorbid conditions.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2021
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Utilization of Complementary and Alternative Therapies in Youth with Developmental Disabilities.Evidence-based complementary and alternative medicine : eCAM · 2019
    Article
  14. Article
  15. Article
  16. Article
  17. Herbal Medicine Treatment for Children with Autism Spectrum Disorder: A Systematic Review.Evidence-based complementary and alternative medicine : eCAM · 2017
    Review
  18. Article
  19. Article
  20. A Randomized, Placebo-controlled Trial of Digestive Enzymes in Children with Autism Spectrum Disorders.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nicholas LofthouseDepartment of Psychiatry, The Ohio State University, 1670 Upham Drive, Columbus, OH 43210, USA.
Robert Hendren
Elizabeth Hurt
L Eugene Arnold
Eric Butter

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the severe and chronic problems associated with Autism Spectrum Disorders (ASD) and the limitations of available treatments, there exists a large public health need for additional interventions. As more parents are inquiring about complementary and alternative treatments (CATs), both parents and practitioners require up-to-date information about them and whether and how to integrate them into treatment. After presenting data on CAT usage patterns for ASD, we review 13 ingestible (i.e., orally administered) and 6 noningestible (i.e., externally administered) CATs for ASD. For each CAT we briefly describe its definition; rationale for use; current research support, limitations, and future directions; safety issues; and whether we currently recommend, not recommend, or find it acceptable for the treatment of ASD. We conclude this paper with recommendations for future research and ten clinical recommendations for practitioners.

Identifiers

PMID23243505
PMCPMC3515887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.