Evidence map›Paper›PMID 23242231›Full record

ReviewJournal of dental research2013

New paradigms on the transport functions of maturation-stage ameloblasts.

R S Lacruz, C E Smith, I Kurtz, M J Hubbard, M L Paine

Abstract readReview
In one paragraph

Review in Journal of dental research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 73 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. The circadian clock in enamel development.International journal of oral science · 2024
    Review
  5. Article
  6. NaFrontiers in physiology · 2023
    Article
  7. Overexpression ofCells · 2022
    Article
  8. Impact of claudin-10 deficiency on amelogenesis: Lesson from a HELIX tooth.Annals of the New York Academy of Sciences · 2022
    Article
  9. Article
  10. Article
  11. Ezh2 knockout in mesenchymal cells causes enamel hyper-mineralization.Biochemical and biophysical research communications · 2021
    Article
  12. The therapeutic importance of acid-base balance.Biochemical pharmacology · 2021
    Review
  13. Review
  14. Article
  15. Article
  16. G protein-coupled receptorThe Journal of biological chemistry · 2020
    Article
  17. Expression Patterns ofFrontiers in cell and developmental biology · 2020
    Article
  18. Article
  19. Article
  20. How pH is regulated during amelogenesis in dental fluorosis.Experimental and therapeutic medicine · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

R S LacruzCenter for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA. rodrigo@usc.edu
C E Smith
I Kurtz
M J Hubbard
M L Paine
University of Southern California · USMcGill University · CAUniversity of California, Los Angeles · USUniversity of Melbourne · AU

Funding

The Biology of NBCe1 in Health and DiseaseR01DK077162 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRA KURTZ · 2007 to 2026
$6.7M
ENAMEL MATRIX PROTEIN INTERACTIONR01DE013404 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PAINE, MICHAEL LANSDELL · 2000 to 2010
$3.5M
BIOLOGY OF SODIUM BICARBONATE TRANSPORTR01DK058563 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KURTZ, IRA · 2001 to 2011
$3.1M
MOLECULAR MECHANISMS FOR EXTRACELLULAR PH CONTROL DURING AMELOGENESISR01DE019629 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PAINE, MICHAEL LANSDELL · 2009 to 2014
$2.9M
Calcium Regulation and Oral HealthR00DE022799 · NIDCR · NEW YORK UNIVERSITY · PI LACRUZ, RODRIGO S. · 2014 to 2016
$728k
CALCIUM REGULATION IN ORAL HEALTHK99DE022799 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LACRUZ, RODRIGO S. · 2012 to 2013
$214k
NIDCR NIH HHS DE013404NIDCR NIH HHS DE019629NIDCR NIH HHS DE022799NIDCR NIH HHS K99 DE022799NIDCR NIH HHS R00 DE022799NIDCR NIH HHS R01 DE013404NIDCR NIH HHS R01 DE019629NIDDK NIH HHS DK058563NIDDK NIH HHS DK077162NIDDK NIH HHS R01 DK058563NIDDK NIH HHS R01 DK077162
6 · The paper itself

Abstract

Fully matured dental enamel is an architecturally and mechanically complex hydroxyapatite-based bioceramic devoid of most of the organic material that was essential in its making. Enamel formation is a staged process principally involving secretory and maturation stages, each associated with major changes in gene expression and cellular function. Cellular activities that define the maturation stage of amelogenesis include ion (e.g., calcium and phosphate) transport and storage, control of intracellular and extracellular pH (e.g., bicarbonate and hydrogen ion movements), and endocytosis. Recent studies on rodent amelogenesis have identified a multitude of gene products that appear to be linked to these cellular activities. This review describes the main cellular activities of these genes during the maturation stage of amelogenesis.

Indexed as

AmeloblastsAmelogenesisCalciumEndocytosisGene Expression RegulationHumansHydrogen-Ion ConcentrationIon TransportPhosphatesCalciumPhosphates

Identifiers

PMID23242231
PMCPMC3545694
OpenAlexW1978994934

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.