Evidence map›Paper›PMID 23241875›Full record

ReviewCurrent opinion in pediatrics2013

Update on recent guidelines for the management of urinary tract infections in children: the shifting paradigm.

Elijah Paintsil

Abstract readReview
In one paragraph

Review in Current opinion in pediatrics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
8.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 60 citations in OpenAlex.

  1. Trial
  2. Article
  3. More than an infection: the ecological puzzle of recurrent urinary tract infections.Frontiers in cellular and infection microbiology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Elijah PaintsilDepartments of Pediatrics and Pharmacology, Yale School of Medicine, New Haven, Connecticut 06520-8064, USA. Elijah.paintsil@yale.edu
Yale University · US

Funding

HIV Nucleoside Analogs Translational Studies: Resistance and MetabolismK08AI074404 · NIAID · YALE UNIVERSITY · PI PAINTSIL, ELIJAH · 2008 to 2012
$629k
NIAID NIH HHS K08 AI074404NIAID NIH HHS K08AI074404
6 · The paper itself

Abstract

purpose of reviewRecent guidelines on the management of urinary tract infections (UTIs) in children have seen a shift from aggressive imaging studies and the use of prophylactic antibiotics to a more restrictive and targeted approach. This review focuses on new additions to the literature on management of UTI from January 2011 to September 2012. RECENT

findingsThe causal relationship between UTI-vesicoureteral reflux (VUR) and renal scarring has been challenged by several studies. Concerns about unnecessary exposure to ionizing radiation, invasiveness of some of the procedures, and risk of infection have also been raised. With improved prenatal ultrasound, a 'top-down' approach to investigating febrile UTI in children using renal bladder ultrasound alone as an initial study has become popular. Several studies have reported that prophylactic antibiotics and imaging studies after first UTI can be reduced substantially without affecting the risk of recurrent UTI or renal scarring. SUMMARY: The use of targeted imaging approach in evaluating febrile UTI in children may lead to improved resource use and reduction of potential harmful procedures and interventions, without affecting outcomes of UTI in children. Providers using current guidelines should endeavor to collect practice-based evidence to validate and inform future guidelines.

Indexed as

Anti-Bacterial AgentsAntibiotic ProphylaxisChildCicatrixHumansKidney DiseasesPractice Guidelines as TopicUrinary Tract InfectionsVesico-Ureteral RefluxAnti-Bacterial Agents

Identifiers

PMID23241875
PMCPMC4880363
OpenAlexW2333222226

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.