Evidence map›Paper›PMID 23241142›Full record

ArticleBMC genomics2012

A genome-wide scan of selective sweeps in two broiler chicken lines divergently selected for abdominal fat content.

Hui Zhang, Shou-Zhi Wang, Zhi-Peng Wang, Yang Da, Ning Wang, Xiao-Xiang Hu, Yuan-Dan Zhang, Yu-Xiang Wang, Li Leng, Zhi-Quan Tang and 1 more

Abstract read
In one paragraph

Article in BMC genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

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0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

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  17. Use of high-density SNP data to identify patterns of diversity and signatures of selection in broiler chickens.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2017
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

11 authors.

Hui ZhangKey Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture, Harbin, PR China.
Shou-Zhi Wang
Zhi-Peng Wang
Yang Da
Ning Wang
Xiao-Xiang Hu
Yuan-Dan Zhang
Yu-Xiang Wang
Li Leng
Zhi-Quan Tang
Hui Li

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGenomic regions controlling abdominal fatness (AF) were studied in the Northeast Agricultural University broiler line divergently selected for AF. In this study, the chicken 60KSNP chip and extended haplotype homozygosity (EHH) test were used to detect genome-wide signatures of AF.

resultsA total of 5357 and 5593 core regions were detected in the lean and fat lines, and 51 and 57 reached a significant level (P<0.01), respectively. A number of genes in the significant core regions, including RB1, BBS7, MAOA, MAOB, EHBP1, LRP2BP, LRP1B, MYO7A, MYO9A and PRPSAP1, were detected. These genes may be important for AF deposition in chickens.

conclusionsWe provide a genome-wide map of selection signatures in the chicken genome, and make a contribution to the better understanding the mechanisms of selection for AF content in chickens. The selection for low AF in commercial breeding using this information will accelerate the breeding progress.

Indexed as

BreedingGenomicsAbdominal FatAnimalsChickensGenetic MarkersHaplotypesQuantitative Trait LociGenetic Markers

Identifiers

PMID23241142
PMCPMC3557156

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.