ArticleInternational journal of clinical practice2013
Risk of cardiovascular disease in HIV, hepatitis C, or HIV/hepatitis C patients compared to the general population.
Article in International journal of clinical practice, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- [Lipid metabolism alterations produced by hepatitis C virus in patients with chronic infection.]Revista espanola de salud publica · 2020Pooled it
- Is hepatitis C associated with atherosclerotic burden? A systematic review and meta-analysis.PloS one · 2014Pooled it
- Cardiovascular Risk in Patients with Chronic Hepatitis C Treated with Direct Acting Antivirals.Journal of clinical medicine · 2022Article
- Standardized Comparison of Cardiovascular Risk Factors Prevalence in Spanish Women and Men Living with HIV and in the General Population.Journal of personalized medicine · 2021Article
- Comparison of Predicted Cardiovascular Risk Profiles by Different CVD Risk-Scoring Algorithms between HIV-1-Infected and Uninfected Adults: A Cross-Sectional Study in Tanzania.HIV/AIDS (Auckland, N.Z.) · 2021Article
- Successful Kidney Transplantation in a Recipient Coinfected with Hepatitis C Genotype 2 and HIV from a Donor Infected with Hepatitis C Genotype 1 in the Direct-Acting Antiviral Era.Case reports in hepatology · 2020Article
- Cardiovascular risk factors in HIV infected individuals: Comparison with general adult control population in Greece.PloS one · 2020Article
- Excess heart age in adult outpatients in routine HIV care.AIDS (London, England) · 2019Article
- Article
- Cardiovascular Disease Risk Assessment in the United States and Low- and Middle-Income Countries Using Predicted Heart/Vascular Age.Scientific reports · 2017Article
- Hepatitis C virus and cardiovascular: A review.Journal of advanced research · 2017Review
- Cardiovascular Risk in HIV-Infected and Uninfected Postmenopausal Minority Women: Use of the Framingham Risk Score.Journal of women's health (2002) · 2017Article
- Association of injection drug use with incidence of HIV-associated non-AIDS-related morbidity by age, 1995-2014.AIDS (London, England) · 2016Article
- Assessment of cardiovascular risk factors in people with HIV infection treated with ART in rural South Africa: a cross sectional study.AIDS research and therapy · 2015Article
- HCV, but not HIV, is a risk factor for cerebral small vessel disease.Neurology(R) neuroimmunology & neuroinflammation · 2014Article
- Metabolic syndrome, diabetes, and cardiovascular risk in HIV.Current HIV/AIDS reports · 2014Review
- Identifying the appropriate comparison group for HIV-infected individuals.Current opinion in HIV and AIDS · 2014Review
- Differences in outpatient care and treatment utilization for patients with HIV/HCV coinfection, HIV, and HCV monoinfection, a cross-sectional study.BMC infectious diseases · 2014Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundAs a result of effective antiretroviral therapy HIV patients are living longer, and their risk of cardiovascular disease (CVD) is a growing concern. It remains unknown whether coinfection with hepatitis C (HCV) changes an HIV person's CVD risk, and how the risks compare to the general population. The objective of this study was to compare the Framingham Risk Score (FRS) and vascular age differences in persons with HIV, HCV or HIV/HCV disease to the general population.
methodsHIV, HCV, and HIV/HCV patients with clinic visits between 2004 and 2009 were sampled from medical clinics in Rochester, NY. Uninfected persons were randomly selected from the National Health and Nutrition Examination Survey (NHANES), and individually matched on gender, race, and age. We stratified by infection group and conducted separate multivariable linear regression analyses between each infection group and the gender, race, and age matched participants from NHANES.
resultsRochester patients (HIV = 239, HCV = 167, HIV/HCV = 182) were compared 3 : 1 with the NHANES participants. After controlling for weight, marital status, current pharmacotherapies and the matching variables of gender, race, and age, HIV/HCV patients had a 2% higher general FRS compared with the general population (p = 0.03), and vascular age differences that were 4.1 years greater (p = .01). HCV patients had a 2.4% higher general FRS than the general population (p < .001), and vascular age differences that were 4.4 years greater (p < .001). CVD risk was elevated but not significantly different between HIV patients and the general population.
conclusionCardiovascular disease risk is elevated among HIV/HCV and HCV infected persons compared with the general population.
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