ArticlePsychopharmacology2013
Over-expectation generated in a complex appetitive goal-tracking task is capable of inducing memory reconsolidation.
Article in Psychopharmacology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed.
- Appetitive Pavlovian conditioned approach to reward location is reduced by both adrenergic and NMDA receptor antagonism at memory reconsolidation.Psychopharmacology · 2026Article
- Drug memory reconsolidation: from molecular mechanisms to the clinical context.Translational psychiatry · 2023Review
- Procedures between training and reactivation influence the destabilization of instrumental sucrose memory.Frontiers in behavioral neuroscience · 2022Article
- Retrieval-Dependent Mechanisms Affecting Emotional Memory Persistence: Reconsolidation, Extinction, and the Space in Between.Frontiers in behavioral neuroscience · 2020Review
- Destabilizing Different Strengths of Fear Memories Requires Different Degrees of Prediction Error During Retrieval.Frontiers in behavioral neuroscience · 2020Article
- On the transition from reconsolidation to extinction of contextual fear memories.Learning & memory (Cold Spring Harbor, N.Y.) · 2017Article
- Reconsolidation and psychopathology: Moving towards reconsolidation-based treatments.Neurobiology of learning and memory · 2017Review
- Reward disrupts reactivated human skill memory.Scientific reports · 2016Article
- Rewriting the valuation and salience of alcohol-related stimuli via memory reconsolidation.Translational psychiatry · 2015Article
- Reconsolidation of a well-learned instrumental memory.Learning & memory (Cold Spring Harbor, N.Y.) · 2014Article
- Ventral tegmental dopamine dysregulation prevents appetitive memory destabilization.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleDiscrepancies in an expected outcome have been demonstrated to result in modification of behaviour in both appetitive and aversive conditioning settings.
objectivesIn this study, we sought to establish whether overexpectation generated from compound conditioning with two previously rewarded stimuli was able to induce memory destabilisation and subsequent reconsolidation in a Pavlovian conditioned approach setting.
resultsIt was shown that 4 days, but not 1 day, of overexpectation training was required to induce memory reconsolidation, and this was disrupted by application of the NMDA subtype of glutamate receptor antagonist MK-801 prior to overexpectation training, but not by MK-801 application 6 h post-training.
conclusionsThese data provide evidence that the memories underlying Pavlovian conditioned approach do undergo reconsolidation and that such reconsolidation can be triggered by overexpectation. Therefore, the updating of appetitive conditioned stimulus and unconditioned stimulus associations underpinning conditioned responding in manners other than extinction training is likely achieved through memory reconsolidation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.