ArticleStroke2013
Psychosocial distress and stroke risk in older adults.
Article in Stroke, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Psychosocial stress and risk of first-ever stroke: a systematic review and meta-analysis.BMC neurology · 2026Pooled it
- The correlation between perceived psychosocial stress and stroke: a meta-analysis.Frontiers in neurology · 2025Pooled it
- Association between depression and stroke risk in adults: a systematic review and meta-analysis.Frontiers in neurology · 2024Pooled it
- Pooled it
- Evidence of perceived psychosocial stress as a risk factor for stroke in adults: a meta-analysis.BMC neurology · 2015Pooled it
- Self-reported experiences of discrimination and health: scientific advances, ongoing controversies, and emerging issues.Annual review of clinical psychology · 2015Pooled it
- Trial
- Association of anti SITH 1 antibody titer with mental stress and intracranial aneurysms.Scientific reports · 2026Article
- Differences in gait biomechanics during level walking between chronic stroke patients with and without depression.Scientific reports · 2026Article
- Article
- Psychosocial wellbeing and short sleep duration among U.S. adults.Sleep & breathing = Schlaf & Atmung · 2025Article
- Psychosocial Stress and Risk for Intracerebral Hemorrhage in the ERICH (Ethnic/Racial Variations of Intracerebral Hemorrhage) Study.Journal of the American Heart Association · 2025Article
- Association between frailty trajectories and stroke incidence among Chinese older adults: evidence from CHARLS 2011-2015.Frontiers in neurology · 2025Article
- The Impact of Self-Perceived Burden on Loneliness in Stroke Patients: The Mediating Role of Rumination.Patient related outcome measures · 2025Article
- Hippocampal and limbic microstructure changes associated with stress across the lifespan: a UK biobank study.Scientific reports · 2024Article
- Causal association between depression and intracranial aneurysms: a bidirectional two-sample Mendelian randomization study.Frontiers in neurology · 2024Article
- Stress-related cellular pathophysiology as a crosstalk risk factor for neurocognitive and psychiatric disorders.BMC neuroscience · 2023Review
- Psychological stress is associated with arterial inflammation in people living with treated HIV infection.Brain, behavior, and immunity · 2023Article
- Impact of dietary intervention on eating behavior after ischemic stroke.Frontiers in nutrition · 2023Article
- Lifestyle and Cognitive Decline in Community-Dwelling Stroke Survivors.Journal of Alzheimer's disease : JAD · 2022Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
background and purposeTo investigate the association of psychosocial distress with risk of stroke mortality and incident stroke in older adults.
methodsData were from the Chicago Health and Aging Project, a longitudinal population-based study conducted in 3 contiguous neighborhoods on the south side of Chicago, IL. Participants were community-dwelling black and non-Hispanic white adults, aged 65 years and older (n=4120 for stroke mortality; n=2649 for incident stroke). Psychosocial distress was an analytically derived composite measure of depressive symptoms, perceived stress, neuroticism, and life dissatisfaction. Cox proportional hazards models examined the association of distress with stroke mortality and incident stroke over 6 years of follow-up.
resultsStroke deaths (151) and 452 incident strokes were identified. Adjusting for age, race, and sex, the hazard ratio (HR) for each 1-SD increase in distress was 1.47 (95% confidence interval [CI]=1.28-1.70) for stroke mortality and 1.18 (95% CI=1.07-1.30) for incident stroke. Associations were reduced after adjustment for stroke risk factors and remained significant for stroke mortality (HR=1.29; 95% CI=1.10-1.52) but not for incident stroke (HR=1.09; 95% CI=0.98-1.21). Secondary analyses of stroke subtypes showed that distress was strongly related to incident hemorrhagic strokes (HR=1.70; 95% CI=1.28-2.25) but not ischemic strokes (HR=1.02; 95% CI=0.91-1.15) in fully adjusted models.
conclusionsIncreasing levels of psychosocial distress are related to excess risk of both fatal and nonfatal stroke in older black and white adults. Additional research is needed to examine pathways linking psychosocial distress to cerebrovascular disease risk.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.