ReviewStem cell reviews and reports2013
Cardiac stem cells and their roles in myocardial infarction.
Review in Stem cell reviews and reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells.European journal of histochemistry : EJH · 2025Article
- Role of HIF-1α-Activated IL-22/IL-22R1/Bmi1 Signaling Modulates the Self-Renewal of Cardiac Stem Cells in Acute Myocardial Ischemia.Stem cell reviews and reports · 2024Article
- Cardiac Stem Cell-Loaded Delivery Systems: A New Challenge for Myocardial Tissue Regeneration.International journal of molecular sciences · 2020Review
- Stress Coping Strategies in the Heart: An Integrated View.Frontiers in cardiovascular medicine · 2018Review
- Transplantation of human villous trophoblasts preserves cardiac function in mice with acute myocardial infarction.Journal of cellular and molecular medicine · 2017Article
- Hypoxia preconditioning promotes cardiac stem cell survival and cardiogenic differentiation in vitro involving activation of the HIF-1α/apelin/APJ axis.Stem cell research & therapy · 2017Article
- Exosomes Generated From iPSC-Derivatives: New Direction for Stem Cell Therapy in Human Heart Diseases.Circulation research · 2017Review
- Long noncoding RNA Braveheart promotes cardiogenic differentiation of mesenchymal stem cells in vitro.Stem cell research & therapy · 2017Article
- Therapeutic use of stem cells for cardiovascular disease.Clinical and translational medicine · 2016Review
- Peroxisome Proliferator-Activated Receptor Gamma Promotes Mesenchymal Stem Cells to Express Connexin43 via the Inhibition of TGF-β1/Smads Signaling in a Rat Model of Myocardial Infarction.Stem cell reviews and reports · 2015Article
- Robust Generation of Cardiomyocytes from Human iPS Cells Requires Precise Modulation of BMP and WNT Signaling.Stem cell reviews and reports · 2015Article
- Formation of a vesicovaginal fistula in a pig model.Research and reports in urology · 2015Article
- Heart regeneration, stem cells, and cytokines.Regenerative medicine research · 2014Review
- microRNA-378 promotes mesenchymal stem cell survival and vascularization under hypoxic-ischemic conditions in vitro.Stem cell research & therapy · 2014Article
- SCF increases cardiac stem cell migration through PI3K/AKT and MMP‑2/‑9 signaling.International journal of molecular medicine · 2014Article
- AT2 receptors targeting cardiac protection post-myocardial infarction.Current hypertension reports · 2014Review
- PEG-maleimide hydrogels for protein and cell delivery in regenerative medicine.Annals of biomedical engineering · 2014Article
- CENP-A is essential for cardiac progenitor cell proliferation.Cell cycle (Georgetown, Tex.) · 2014Article
- Adult stem cells and cardiac regeneration.Stem cell reviews and reports · 2013Article
- Cortisol stimulates proliferation and apoptosis in the late gestation fetal heart: differential effects of mineralocorticoid and glucocorticoid receptors.American journal of physiology. Regulatory, integrative and comparative physiology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Myocardial infarction leads to loss of cardiomyocytes, scar formation, ventricular remodeling and eventually deterioration of heart function. Over the past decade, stem cell therapy has emerged as a novel strategy for patients with ischemic heart disease and its beneficial effects have been demonstrated by substantial preclinical and clinical studies. Efficacy of several types of stem cells in the therapy of cardiovascular diseases has already been evaluated. However, repair of injured myocardium through stem cell transplantation is restricted by critical safety issues and ethic concerns. Recently, the discovery of cardiac stem cells (CSCs) that reside in the heart itself brings new prospects for myocardial regeneration and reconstitution of cardiac tissues. CSCs are positive for various stem cell markers and have the potential of self-renewal and multilineage differentiation. They play a pivotal role in the maintenance of heart homeostasis and cardiac repair. Elucidation of their biological characteristics and functions they exert in myocardial infarction are very crucial to further investigations on them. This review will focus on the field of cardiac stem cells and discuss technical and practical issues that may involve in their clinical applications in myocardial infarction.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.