ArticleNature chemical biology2013
A public-private partnership to unlock the untargeted kinome.
Article in Nature chemical biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed.
- Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships.European journal of medicinal chemistry · 2024Article
- Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships.bioRxiv : the preprint server for biology · 2023Article
- Utilization of Supervised Machine Learning to Understand Kinase Inhibitor Toxophore Profiles.International journal of molecular sciences · 2023Article
- An update regarding the role of WNK kinases in cancer.Cell death & disease · 2022Review
- Improving the Prediction of Potential Kinase Inhibitors with Feature Learning on Multisource Knowledge.Interdisciplinary sciences, computational life sciences · 2022Article
- Understudied proteins: opportunities and challenges for functional proteomics.Nature methods · 2022Article
- Facing small and biased data dilemma in drug discovery with enhanced federated learning approaches.Science China. Life sciences · 2022Article
- GAK and PRKCD are positive regulators of PRKN-independent mitophagy.Nature communications · 2021Article
- KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases.BMC bioinformatics · 2021Article
- The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification.International journal of molecular sciences · 2021Article
- A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation.Journal of medicinal chemistry · 2020Article
- Kinome Profiling of Primary Endometrial Tumors Using Multiplexed Inhibitor Beads and Mass Spectrometry Identifies SRPK1 as Candidate Therapeutic Target.Molecular & cellular proteomics : MCP · 2020Article
- Crystal Structure and Inhibitor Identifications Reveal Targeting Opportunity for the Atypical MAPK Kinase ERK3.International journal of molecular sciences · 2020Article
- Cdc-Like Kinases (CLKs): Biology, Chemical Probes, and Therapeutic Potential.International journal of molecular sciences · 2020Review
- Cataloguing the dead: breathing new life into pseudokinase research.The FEBS journal · 2020Review
- Three-Dimensional Interactions Analysis of the Anticancer Target c-Src Kinase with Its Inhibitors.Cancers · 2020Review
- New Insights into 4-Anilinoquinazolines as Inhibitors of Cardiac Troponin I-Interacting Kinase (TNNi3K).Molecules (Basel, Switzerland) · 2020Article
- The identification and characterisation of autophagy inhibitors from the published kinase inhibitor sets.The Biochemical journal · 2020Article
- The kinase polypharmacology landscape of clinical PARP inhibitors.Scientific reports · 2020Article
- Theoretical Exploring Selective-Binding Mechanisms of JAK3 by 3D-QSAR, Molecular Dynamics Simulation and Free Energy Calculation.Frontiers in molecular biosciences · 2020Article
Corrections and comments
- Commented on byRisky business.2013
Authors and funding
16 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
23238671What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.