ReviewCritical reviews in oncogenesis2013
Tumor-stromal interactions in pancreatic cancer.
Review in Critical reviews in oncogenesis, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed.
- Sonoporation for Augmenting Chemotherapy of Pancreatic Ductal Adenocarcinoma.Methods in molecular biology (Clifton, N.J.) · 2020Trial
- Trial
- Advanced glycation end product (AGE) targeting antibody SIWA318H is efficacious in preclinical models for pancreatic cancer.Scientific reports · 2023Article
- Article
- Species-Deconvolved Proteomics forJournal of proteome research · 2023Article
- Cancer-associated fibroblast-dependent and -independent invasion of gastric cancer cells.Journal of cancer research and clinical oncology · 2023Article
- ID1 marks the tumorigenesis of pancreatic ductal adenocarcinoma in mouse and human.Scientific reports · 2022Article
- Review
- Cell-to-cell interaction analysis of prognostic ligand-receptor pairs in human pancreatic ductal adenocarcinoma.Biochemistry and biophysics reports · 2021Article
- Collagen Organization Does Not Influence T-Cell Distribution in Stroma of Human Pancreatic Cancer.Cancers · 2021Article
- Drug-exposed cancer-associated fibroblasts facilitate gastric cancer cell progression following chemotherapy.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2021Article
- Seven-gene signature on tumor microenvironment for predicting the prognosis of patients with pancreatic cancer.Gland surgery · 2021Article
- Triptolide targets super-enhancer networks in pancreatic cancer cells and cancer-associated fibroblasts.Oncogenesis · 2020Article
- Single-cell transcriptome analysis of tumor and stromal compartments of pancreatic ductal adenocarcinoma primary tumors and metastatic lesions.Genome medicine · 2020Article
- Inactivation of Pancreatic Stellate Cells by Exendin-4 Inhibits the Migration and Invasion of Pancreatic Cancer Cells.OncoTargets and therapy · 2020Article
- Polymer nanomedicines.Advanced drug delivery reviews · 2020Review
- 3D approaches to model the tumor microenvironment of pancreatic cancer.Theranostics · 2020Review
- The phenanthrene derivative PJ34 exclusively eradicates human pancreatic cancer cells in xenografts.Oncotarget · 2019Article
- The Janus Face of Tumor Microenvironment Targeted by Immunotherapy.International journal of molecular sciences · 2019Review
- Development of apratoxin S10 (Apra S10) as an anti-pancreatic cancer agent and its preliminary evaluation in an orthotopic patient-derived xenograft (PDX) model.Investigational new drugs · 2019Article
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Authors and funding
4 authors.
Funding
Abstract
The tumor associated stroma has been described in recent years as being complicit in tumor growth in pancreatic cancer. The stroma hosts a variety of components of both cellular and molecular makeup. In normal tissues, the stroma provides nutrients and regulatory signals for proper cellular polarity and function. However, following oncogenic transformation, the stromal compartment is conscripted to provide stimulatory signals and protection to tumor cells. It is these tumor-stromal interactions that are currently of great therapeutic interest. Several key reports have suggested that therapeutic targeting of the tumor-stromal interactions in pancreatic cancer has the potential to offer survival benefit. In this review, we will discuss the tumor-stromal interactions that contribute to tumor growth and progression, and ways in which we might counter these interactions.
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