ArticleRespiratory research2012
Elevated cardiovascular risk among adults with obstructive and restrictive airway functioning in the United States: a cross-sectional study of the National Health and Nutrition Examination Survey from 2007-2010.
Article in Respiratory research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 39 citations in OpenAlex.
- Clustering-based COPD subtypes have distinct longitudinal outcomes and multi-omics biomarkers.BMJ open respiratory research · 2022Observational
- Lung Function in Young Adults and Risk of Cardiovascular Events Over 29 Years: The CARDIA Study.Journal of the American Heart Association · 2018Article
- Association of lung function with cardiovascular risk: a cohort study.Respiratory research · 2018Article
- Airway obstruction and the risk of myocardial infarction and death from coronary heart disease: a national health examination survey with a 33-year follow-up period.European journal of epidemiology · 2018Article
- Ischemic ECG abnormalities are associated with an increased risk for death among subjects with COPD, also among those without known heart disease.International journal of chronic obstructive pulmonary disease · 2017Article
- Pulmonary artery to aorta ratio is associated with cardiac structure and functional changes in mild-to-moderate COPD.International journal of chronic obstructive pulmonary disease · 2017Article
- Article
- Incidence of stroke and stroke subtypes in chronic obstructive pulmonary disease.European journal of epidemiology · 2016Article
- Loss of Lung Health from Young Adulthood and Cardiac Phenotypes in Middle Age.American journal of respiratory and critical care medicine · 2015Article
- Prevalence of Spirometrically-defined Restrictive Ventilatory Defect in Korea: The Fourth-2, 3, and Fifth Korean National Health and Nutrition Examination Survey, 2008-2012.Journal of Korean medical science · 2015Article
- Central arterial stiffness is increased among subjects with severe and very severe COPD: report from a population-based cohort study.European clinical respiratory journal · 2015Article
- Article
- Co-morbidities are the key nominators of the health related quality of life in mild and moderate COPD.BMC pulmonary medicine · 2014Observational
- Acute exacerbation of chronic obstructive pulmonary disease: cardiovascular links.BioMed research international · 2014Review
- Relationships among smoking habits, airflow limitations, and metabolic abnormalities in school workers.PloS one · 2013Article
- Development and validation of a model to predict the risk of exacerbations in chronic obstructive pulmonary disease.International journal of chronic obstructive pulmonary disease · 2013Article
- All-cause and cause-specific mortality by spirometric pattern and sex - a population-based cohort study.Therapeutic advances in respiratory diseaseArticle
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundReasons for the excess risk for cardiovascular disease among people with chronic obstructive pulmonary disease remain unclear. Our objective was to examine the cardiovascular risk profile for adults with obstructive and restrictive impairments of lung functioning in a representative sample of adults from the United States.
methodsWe used data from adults aged 20-79 years who participated in the National Health and Nutrition Examination Survey from 2007 to 2010 and had a pulmonary function test. The severity of obstructive impairment was defined by adapting the Global Initiative for Chronic Obstructive Lung Disease criteria.
resultsAmong 7249 participants, 80.9% had a normal pulmonary function test, 5.7% had a restrictive impairment, 7.9% had mild obstructive impairment, and 5.5% had moderate or severe/very severe obstructive impairment. Participants with obstructive impairment had high rates of smoking and increased serum concentrations of cotinine. Compared to participants with normal pulmonary functioning, participants with at least moderate obstructive impairment had elevated concentrations of C-reactive protein but lower concentrations of total cholesterol and non-high-density lipoprotein cholesterol. Among participants aged 50-74 years, participants with at least a moderate obstructive impairment or a restrictive impairment had an elevated predicted 10-year risk for cardiovascular disease.
conclusionsThe high rates of smoking among adults with impaired pulmonary functioning, particularly those with obstructive impairment, point to a need for aggressive efforts to promote smoking cessation in these adults. In addition, adults with restrictive impairment may require increased attention to and fine-tuning of their cardiovascular risk profile.
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