ArticleInternational journal of clinical and experimental pathology2013
Endomyocardial biopsy for monitoring heart transplant patients: 11-years-experience at a german heart center.
Article in International journal of clinical and experimental pathology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- MicroRNAs and their role in heart transplantation insights into rejection mechanisms: A narrative review.JHLT open · 2026Article
- Cellular Rejection Post-Cardiac Transplantation: A 13-Year Single Unicentric Study.Medicina (Kaunas, Lithuania) · 2025Article
- The role of endomyocardial biopsy for surveillance of cardiac allograft rejection: time to move on?Cardiology journal · 2025Article
- Article
- Advancements in Heart Transplantation: Donor-Derived Cell-Free DNA as Next-Generation Biomarker.Cureus · 2024Review
- Right or left endomyocardial biopsy? A systematic review with meta-analysis about complications and safety.JHLT open · 2023Review
- Revisiting transplant immunology through the lens of single-cell technologies.Seminars in immunopathology · 2023Review
- Endothelial Stromal PD-L1 (Programmed Death Ligand 1) Modulates CD8Circulation. Heart failure · 2021Article
- Case report of a coronary artery-right ventricular fistula following repeat endomyocardial biopsies in a heart transplant patient.European heart journal. Case reports · 2021Article
- Usefulness of speckle tracking echocardiography and biomarkers for detecting acute cellular rejection after heart transplantation.Cardiovascular ultrasound · 2021Article
- Nuclear Osteopontin Is a Marker of Advanced Heart Failure and Cardiac Allograft Vasculopathy: Evidence From Transplant and Retransplant Hearts.Frontiers in physiology · 2020Article
- Magnetic resonance imaging of the transplanted pediatric heart as a potential predictor of rejection.World journal of transplantation · 2016Article
- Endomyocardial biopsy via the femoral access - still safe and valuable diagnostic tool.BMC cardiovascular disorders · 2016Article
- Successful venous angioplasty of superior vena cava syndrome after heart transplantation.Case reports in cardiology · 2014Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHeart transplantation (HTX) has become an established therapy for patients with end-stage heart failure. Endomyocardial biopsy (EMB) still represents the gold standard for routine surveillance of heart transplant rejection. The objective of this article is to report our experience regarding the use of EMB in monitoring heart transplant recipients.
methodsWe evaluated retrospectively all patients who underwent orthotopic HTX between 2000 and 2011 at our hospital. From all patients, we created a follow-up, determined the number of EMB events and described the complications associated with this procedure.
resultsHTX was performed in 142 cases at our center in the last 11 years (1.3% of the total of 10693 cardiac surgical operations in that period). Further 9 patients visited our department for monitoring after HTX performed at an external center (total: 151). For all patients, a total of 1896 EMB events have been recorded. The majority of biopsies were performed through the right internal jugular vein. The overall complication rate was 1% (n=19).
conclusionsThe histological examination of right ventricular EMB still represents the gold standard of care for cardiac allograft rejection monitoring. EMB is an invasive, but safe and dedicated diagnostic procedure. However, the usefulness of recent non-invasive diagnostic approaches as an adjunct tool in monitoring for rejection remains to be further analyzed.
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