Evidence map›Paper›PMID 23236382›Full record

ArticlePloS one2012

Delayed contrast-enhanced MRI of the coronary artery wall in takayasu arteritis.

Christopher Schneeweis, Bernhard Schnackenburg, Matthias Stuber, Alexander Berger, Udo Schneider, Jing Yu, Rolf Gebker, Robert G Weiss, Eckart Fleck, Sebastian Kelle

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Review
  3. SCMR expert consensus statement for cardiovascular magnetic resonance of acquired and non-structural pediatric heart disease.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022
    Review
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  6. Observational
  7. Article
  8. Article
  9. Imaging in Giant Cell Arteritis.Current rheumatology reports · 2015
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Christopher SchneeweisDepartment of Internal Medicine/Cardiology, Deutsches Herzzentrum Berlin, Berlin, Germany.
Bernhard Schnackenburg
Matthias Stuber
Alexander Berger
Udo Schneider
Jing Yu
Rolf Gebker
Robert G Weiss
Eckart Fleck
Sebastian Kelle
Deutsches Herzzentrum der Charité · DECentre d'Imagerie BioMedicale · CHCharité - Universitätsmedizin Berlin · DEJohns Hopkins Medicine · USPhilips (Germany) · DEResonance Research (United States) · US

Funding

Non-Invasive Measures of Regional Coronary Endothelial Function by 3T MRIR01HL084186 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI STUBER, MATTHIAS · 2006 to 2010
$2.3M
NHLBI NIH HHS R01 HL084186NHLBI NIH HHS R01HL084186
6 · The paper itself

Abstract

backgroundTakayasu arteritis (TA) is a rare form of chronic inflammatory granulomatous arteritis of the aorta and its major branches. Late gadolinium enhancement (LGE) with magnetic resonance imaging (MRI) has demonstrated its value for the detection of vessel wall alterations in TA. The aim of this study was to assess LGE of the coronary artery wall in patients with TA compared to patients with stable CAD.

methodsWe enrolled 9 patients (8 female, average age 46±13 years) with proven TA. In the CAD group 9 patients participated (8 male, average age 65±10 years). Studies were performed on a commercial 3T whole-body MR imaging system (Achieva; Philips, Best, The Netherlands) using a 3D inversion prepared navigator gated spoiled gradient-echo sequence, which was repeated 34-45 minutes after low-dose gadolinium administration.

resultsNo coronary vessel wall enhancement was observed prior to contrast in either group. Post contrast, coronary LGE on IR scans was detected in 28 of 50 segments (56%) seen on T2-Prep scans in TA and in 25 of 57 segments (44%) in CAD patients. LGE quantitative assessment of coronary artery vessel wall CNR post contrast revealed no significant differences between the two groups (CNR in TA: 6.0±2.4 and 7.3±2.5 in CAD; p = 0.474).

conclusionOur findings suggest that LGE of the coronary artery wall seems to be common in patients with TA and similarly pronounced as in CAD patients. The observed coronary LGE seems to be rather unspecific, and differentiation between coronary vessel wall fibrosis and inflammation still remains unclear.

Indexed as

AdultAgedCoronary Artery DiseaseCoronary VesselsFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesTakayasu Arteritis

Identifiers

PMID23236382
PMCPMC3517571
OpenAlexW2037577732

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.