Evidence map›Paper›PMID 23236345›Full record

Trial reportPloS one2012

The Cameroon Mobile Phone SMS (CAMPS) trial: a randomized trial of text messaging versus usual care for adherence to antiretroviral therapy.

Lawrence Mbuagbaw, Lehana Thabane, Pierre Ongolo-Zogo, Richard T Lester, Edward J Mills, Marek Smieja, Lisa Dolovich, Charles Kouanfack

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01247181 (Improving Adherence to HAART Using Mobile Phone Text Messages), which is not on this map. Cited by 138 papers, 34 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 34 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01247181 nacompletednot on this map

Improving Adherence to HAART Using Mobile Phone Text Messages

TypeinterventionalSponsorYaounde Central HospitalRan2010 to 2011Enrolled200ConditionsAdherence, HIVArmsMobile phone text message, Usual care
3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 34 syntheses or guidelines pooled it.

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  3. Mobile phone-based interventions for improving contraception use.The Cochrane database of systematic reviews · 2023
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  4. Smartphone Apps for Domestic Violence Prevention: A Systematic Review.International journal of environmental research and public health · 2023
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  20. Strengthening Delivery of Health Services Using Digital Devices.Global health, science and practice · 2018
    Pooled it

78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lawrence MbuagbawCentre for the Development of Best Practices in Health (CDBPH), Yaoundé Central Hospital, Yaoundé, Centre, Cameroon. mbuagblc@mcmaster.ca
Lehana Thabane
Pierre Ongolo-Zogo
Richard T Lester
Edward J Mills
Marek Smieja
Lisa Dolovich
Charles Kouanfack

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

backgroundMobile phone technology is a novel way of delivering health care and improving health outcomes. This trial investigates the use of motivational mobile phone text messages (SMS) to improve adherence to antiretroviral therapy (ART) over six months. METHODOLOGY/PRINCIPAL

findingsCAMPS was a single-site randomized two-arm parallel design trial in Yaoundé, Cameroon. We enrolled and randomized HIV-positive adults on ART, aged 21 years and above to receive a weekly standardized motivational text message versus usual care alone. The primary outcome was adherence measured using a visual analogue scale (VAS), number of doses missed (in the week preceding the interview) and pharmacy refill data. Outcomes were measured at 3 and 6 months. Service providers and outcome assessors were blinded to allocation. Analysis was by intention-to-treat. Between November and December 2010, 200 participants were randomized, with 101 in the intervention group and 99 in the control group. At 6 months, overall retention was 81.5%. We found no significant effect on adherence by VAS>95% (risk ratio [RR] 1.06, 95% confidence interval [CI] 0.89, 1.29; p = 0.542; reported missed doses (RR 1.01, 95% CI 0.87, 1.16; p>0.999) or number of pharmacy refills (mean difference [MD] 0.1, 95% CI: 0.23, 0.43; p = 0.617. One participant in the intervention arm reported a possible disclosure of status. CONCLUSIONS/SIGNIFICANCE: Standardized motivational mobile phone text messages did not significantly improve adherence to ART in this study. Other types of messaging or longer term studies are recommended. REGISTRATION: 1. Pan-African Clinical Trials Registry; PACTR201011000261458 2. Clinicaltrials.gov; NCT01247181.

Indexed as

Medication AdherenceReminder SystemsText MessagingAdultAnti-HIV AgentsAnti-Retroviral AgentsCameroonFemaleHIV InfectionsHIV SeropositivityHumansMaleMiddle AgedMotivationPatient SatisfactionTreatment OutcomeAnti-HIV AgentsAnti-Retroviral Agents

Identifiers

PMID23236345
PMCPMC3516507

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.