Evidence map›Paper›PMID 23236081›Full record

ArticleSchizophrenia bulletin2014

Social deprivation, inequality, and the neighborhood-level incidence of psychotic syndromes in East London.

James B Kirkbride, Peter B Jones, Simone Ullrich, Jeremy W Coid

Open access · bronzeAbstract read
In one paragraph

Article in Schizophrenia bulletin, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 11 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 11 syntheses or guidelines pooled it, 271 citations in OpenAlex.

  1. A meta-analysis of the role of neighborhood deprivation in psychotic disorders.Social psychiatry and psychiatric epidemiology · 2025
    Pooled it
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  4. Social Fragmentation and Schizophrenia: A Systematic Review.The Journal of clinical psychiatry · 2021
    Pooled it
  5. The ethnic density effect in psychosis: a systematic review and multilevel meta-analysis.The British journal of psychiatry : the journal of mental science · 2021
    Pooled it
  6. Perceived discrimination and psychosis: a systematic review of the literature.Social psychiatry and psychiatric epidemiology · 2019
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  14. Synergistic pathways to psychosis: understanding developmental risk and resilience factors.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

James B KirkbrideTo whom correspondence should be addressed; Department of Psychiatry, Herchel Smith Building University of Cambridge, Forvie Site, Robinson Way, Cambridge, CB2 0SZ, UK; tel: 01223 336966, fax: 01223 336 968, e-mail: jbk25@cam.ac.uk.
Peter B Jones
Simone Ullrich
Jeremy W Coid
St Bartholomew's Hospital · GBUniversity of Cambridge · GB

Funding

Department of Health RP-PG-0407-10500Department of Health RP-PG-0606-1335Medical Research Council G0001354Medical Research Council G1000183Wellcome Trust 085540
6 · The paper itself

Abstract

Although urban birth, upbringing, and living are associated with increased risk of nonaffective psychotic disorders, few studies have used appropriate multilevel techniques accounting for spatial dependency in risk to investigate social, economic, or physical determinants of psychosis incidence. We adopted Bayesian hierarchical modeling to investigate the sociospatial distribution of psychosis risk in East London for DSM-IV nonaffective and affective psychotic disorders, ascertained over a 2-year period in the East London first-episode psychosis study. We included individual and environmental data on 427 subjects experiencing first-episode psychosis to estimate the incidence of disorder across 56 neighborhoods, having standardized for age, sex, ethnicity, and socioeconomic status. A Bayesian model that included spatially structured neighborhood-level random effects identified substantial unexplained variation in nonaffective psychosis risk after controlling for individual-level factors. This variation was independently associated with greater levels of neighborhood income inequality (SD increase in inequality: Bayesian relative risks [RR]: 1.25; 95% CI: 1.04-1.49), absolute deprivation (RR: 1.28; 95% CI: 1.08-1.51) and population density (RR: 1.18; 95% CI: 1.00-1.41). Neighborhood ethnic composition effects were associated with incidence of nonaffective psychosis for people of black Caribbean and black African origin. No variation in the spatial distribution of the affective psychoses was identified, consistent with the possibility of differing etiological origins of affective and nonaffective psychoses. Our data suggest that both absolute and relative measures of neighborhood social composition are associated with the incidence of nonaffective psychosis. We suggest these associations are consistent with a role for social stressors in psychosis risk, particularly when people live in more unequal communities.

Indexed as

Residence CharacteristicsSocial EnvironmentUrban PopulationAdolescentAdultBlack PeopleFemaleHumansIncidenceLondonMaleMiddle AgedPsychotic DisordersRiskSocioeconomic FactorsSyndromeBayesian modelingdeprivationepidemiologyinequalitypsychosisschizophreniasocial environmenturban

Identifiers

PMID23236081
PMCPMC3885290
OpenAlexW2163503308

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.