Evidence map›Paper›PMID 23235654›Full record

SynthesisThe Cochrane database of systematic reviews2012

Transparent cap colonoscopy versus standard colonoscopy to improve caecal intubation.

Jenna Morgan, Kathryn Thomas, Heather Lee-Robichaud, Richard L Nelson, Sarah Braungart

Registry-linked trialOpen access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03160859 (Prospective RCT of Water Exchange), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03160859 nacompletednot on this mapstarted 2018, after this paper: background citation

Prospective RCT of Water Exchange (WE) vs. WE Plus Cap-Assisted Colonoscopy

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2018 to 2022Enrolled280ConditionsUnsedated Colonoscopy, Water Exchange Colonoscopy, Cap, Colonoscopy PainArmsControl, Study method
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Trial
  3. The use of a transparent cap in sigmoidoscopy-A randomized controlled clinical trial on pain, time and success rate.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2017
    Trial
  4. Review
  5. Article
  6. Standards of diagnostic colonoscopy for early-stage neoplasia: Recommendations by an Asian private group.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2019
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jenna MorganDepartment of General Surgery, Northern General Hospital, Sheffield, UK.jenna.morgan@doctors.org.uk.
Kathryn Thomas
Heather Lee-Robichaud
Richard L Nelson
Sarah Braungart
Northern General Hospital · GBNorthern Lincolnshire and Goole Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundColonoscopy is considered the gold-standard investigation for screening and diagnosis of colorectal cancer. It is also becoming increasingly desirable for assessment, management, diagnosis and follow-up of other colorectal diseases, such as inflammatory bowel diseases and acute diverticulitis. Hence, due to the increasing demand for colonoscopy, devices to advance examination techniques are highly sought-after and the colonoscope with the transparent cap could be one of these.

objectivesTo identify and review all relevant data in order to determine whether colonoscopy with a transparent cap is a more effective diagnostic tool than colonoscopy. SEARCH

methodsWe searched the MEDLINE, EMBASE and CINAHL databases, and the Cochrane Central Register of Controlled Trials for all randomised controlled trials (RCTs) comparing the use of colonoscopy with a transparent cap with standard colonoscopy. SELECTION CRITERIA: Studies were included if they were randomised controlled trials which compared the use of colonoscopy with a transparent cap with standard colonoscopy. DATA COLLECTION AND ANALYSIS: Data on study methods, participants, interventions used and outcomes measured was extracted from each study. Data was entered into the Cochrane Review Manager software (RevMan 5.0, 2008) and analysed using Cochrane MetaView. MAIN

resultsIn the present meta-analysis, we considered 14 randomised controlled trials so far published. The findings of our work indicate that colonoscopy with transparent cap has a faster caecal intubation time when compared with standard colonoscopy. Reviewing studies individually would also seem to favour colonoscopy with transparent cap for polyp detection rate and pain during procedure but due to lack of comparable data meta-analysis was not feasible. AUTHORS'

conclusionsThis review suggests that a transparent cap on the end of the colonoscope may give a marginally faster caecal intubation time compared with standard colonoscopy. It also suggests that there is a better polyp detection rate and less pain with the cap. However, the authors feel that further randomised controlled trials in this area would provide more clinically significant information on this adjunct to colonoscopy.

Indexed as

AdenomaCecumColonoscopesColonoscopyEquipment DesignHumansIntestinal NeoplasmsIntestinal PolypsIntubation, GastrointestinalRandomized Controlled Trials as TopicTime Factors

Identifiers

PMID23235654
PMCPMC7105905
OpenAlexW2123148132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.