ArticleRNA biology2013
The A-nucleotide preference of HIV-1 in the context of its structured RNA genome.
Article in RNA biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- APOBEC3G Antagonism by Vif, or When Structure Meets Biological and Evolutionary Studies.Annual review of virology · 2025Review
- Mapping the structural landscape of the yeast Ty3 retrotransposon RNA genome.Nucleic acids research · 2024Article
- Silent codon positions in the A-rich HIV RNA genome that do not easily become A: Restrictions imposed by the RNA sequence and structure.Virus evolution · 2022Article
- Biased Mutation and Selection in RNA Viruses.Molecular biology and evolution · 2021Article
- A comprehensive analysis of genome composition and codon usage patterns of emerging coronaviruses.Virus research · 2020Article
- Codon usage similarity between viral and some host genes suggests a codon-specific translational regulation.Heliyon · 2020Article
- Evolution of Subgenomic RNA Shapes Dengue Virus Adaptation and Epidemiological Fitness.iScience · 2019Article
- Within-patient mutation frequencies reveal fitness costs of CpG dinucleotides and drastic amino acid changes in HIV.PLoS genetics · 2018Article
- RNA Structure-A Neglected Puppet Master for the Evolution of Virus and Host Immunity.Frontiers in immunology · 2018Review
- Euclidean Distance Analysis Enables Nucleotide Skew Analysis in Viral Genomes.Computational and mathematical methods in medicine · 2018Article
- Nucleotide composition of the Zika virus RNA genome and its codon usage.Virology journal · 2016Article
- Full-length RNA structure prediction of the HIV-1 genome reveals a conserved core domain.Nucleic acids research · 2015Article
- Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA.Nature immunology · 2015Article
- RNA structure. Structure of the HIV-1 RNA packaging signal.Science (New York, N.Y.) · 2015Article
- On the biased nucleotide composition of the human coronavirus RNA genome.Virus research · 2015Article
- Large-scale nucleotide optimization of simian immunodeficiency virus reduces its capacity to stimulate type I interferon in vitro.Journal of virology · 2014Article
- In vivo SELEX of single-stranded domains in the HIV-1 leader RNA.Journal of virology · 2014Article
- Comparison of SIV and HIV-1 genomic RNA structures reveals impact of sequence evolution on conserved and non-conserved structural motifs.PLoS pathogens · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A bipartition of HIV-1 RNA genome sequences into single- and double-stranded nucleotides is possible based on the secondary structure model of a complete 9 kb genome. Subsequent analysis revealed that the well-known lentiviral property of A-accumulation is profoundly present in single-stranded domains, yet absent in double-stranded domains. Mutational rate analysis by means of an unrestricted model of nucleotide substitution suggests the presence of an evolutionary equilibrium to preserve this biased nucleotide distribution.
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