Trial reportEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2012
Long-term effect of maternal xylitol exposure on their children's caries prevalence.
Trial report in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 3 syntheses or guidelines pooled it, 11 citations in OpenAlex.
- Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood caries.The Cochrane database of systematic reviews · 2024Pooled it
- Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood caries.The Cochrane database of systematic reviews · 2019Pooled it
- Effect of Antimicrobial Interventions on the Oral Microbiota Associated with Early Childhood Caries.Pediatric dentistryPooled it
- Maternal xylitol and mutans streptococci transmission.Evidence-based dentistry · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo evaluate the long-term outcome of a mother-child project in which mothers (n=173) with high counts of salivary mutans streptococci were randomly assigned to daily chewing gums containing xylitol (A), chlorhexidine/ xylitol/sorbitol (B), or sodium fluoride/xylitol/sorbitol (C) for one year, when the child was between 6 and 18 months.
methods140 of the off-springs were re-examined at the age of 10 years and 204 children of mothers with low counts of salivary mutans streptococci three months after delivery served as positive controls (D). Caries was scored in the young permanent dentition on enamel (noncavitated) and dentine (cavitated) levels.
resultsThe long-term attrition rate was 15%. The overall caries prevalence in the combined groups at 10 years of age was 31% (21% non-cavitated; 17% cavitated) with a mean DS of 0.7 (SD 1.3). No significant differences were found between the three experimental groups (A-C), or when compared with the control group. A statistically significant (p<0.05) positive relationship between the levels of salivary mutans streptococci at 18 months of age and the caries experience at the age of 10 years was disclosed for all groups combined.
conclusionNo beneficial longterm effects of maternal xylitol gum exposure on their children's dental health were demonstrated when compared with gums containing chlorhexidine and fluoride.
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