Evidence map›Paper›PMID 23233196›Full record

ArticleJapanese journal of ophthalmology2013

Recovery from deepening of the upper eyelid sulcus after switching from bimatoprost to latanoprost.

Rei Sakata, Shiroaki Shirato, Kazunori Miyata, Makoto Aihara

Abstract read
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In one paragraph

Article in Japanese journal of ophthalmology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Oculoplastic Challenges in Patients with Glaucoma.Turkish journal of ophthalmology · 2025
    Review
  5. Article
  6. From Eye Care to Hair Growth: Bimatoprost.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. Observational
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Review
  16. Prostaglandin-associated periorbitopathy in latanoprost users.Clinical ophthalmology (Auckland, N.Z.) · 2015
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Rei SakataDepartment of Ophthalmology, Tokyo Metropolitan Geriatric Hospital, 35-2 Sakaecho, Itabashi, Tokyo, Japan. reisakata-tky@umin.ac.jp
Shiroaki Shirato
Kazunori Miyata
Makoto Aihara
Miyata Eye Hospital · JPThe University of Tokyo · JPTokyo Metropolitan Geriatric Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAlthough useful for reducing intraocular pressure (IOP), bimatoprost (BIM) can cause deepening of the upper eyelid sulcus (DUES), one of the symptoms of prostaglandin-associated periorbitopathy (PAP). We investigated recovery from BIM-induced DUES after switching treatment to latanoprost (LAT).

designProspective, observer-masked, open-label study.

methodsTwenty-five Japanese patients suffering from primary open-angle glaucoma treated with LAT in both eyes for longer than 6 months and requiring further IOP reduction were prospectively enrolled in the study. During the first 6 months after the switch to BIM, 15 of the 25 patients (60 %) developed DUES. Among these patients, 13 were switched back to LAT and re-examined for DUES at 2-month intervals for an additional 6 months.

resultsTwo months after the switch back to LAT, for 11 of the 13 patients (85 %) the DUES symptoms had either decreased or disappeared, and this was maintained for at least 6 months. During this time, 6 of 8 patients (75 %) subjectively positive for DUES self-reported a decrease in DUES.

conclusionsAlthough DUES is a frequent side effect of treatment with BIM, switching to LAT may reverse the condition for most patients.

Indexed as

AdultAgedAmidesAntihypertensive AgentsBimatoprostCloprostenolDrug SubstitutionEyelid DiseasesEyelidsFemaleGlaucoma, Open-AngleHumansIntraocular PressureLatanoprostMaleMiddle AgedAmidesAntihypertensive AgentsBimatoprostCloprostenolLatanoprostProstaglandins F, Synthetic

Identifiers

PMID23233196
OpenAlexW2020816860

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.