ArticleJournal of biomedical optics2012
Effects of light scattering on optical-resolution photoacoustic microscopy.
Article in Journal of biomedical optics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Computational and experimental investigation of nanoparticle effects on tissue optical properties and optical coherence tomography imaging.Biomedical optics express · 2026Article
- Development of a Dual Photoacoustic-Ultrasound Imaging System: Current Status and Future Perspectives.Sensors (Basel, Switzerland) · 2026Review
- Intensity correlation scan (IC-scan) technique to characterize the optical nonlinearities of scattering media.Scientific reports · 2023Article
- Imaging deeper than the transport mean free path with multiphoton microscopy.Biomedical optics express · 2022Article
- Neural Network for Enhancing Microscopic Resolution Based on Images from Scanning Electron Microscope.Sensors (Basel, Switzerland) · 2021Article
- Photophysical and Photoacoustic Properties of π-Extended Curcumin Dyes. Effects of the Terminal Dimethylamino Electron-donor and the Bridging Aryl Ring.Photochemistry and photobiology · 2019Article
- Molecular Photoacoustic Contrast Agents: Design Principles & Applications.Photochemistry and photobiology · 2018Review
- Time-reversed ultrasonically encoded optical focusing through highly scattering ex vivo human cataractous lenses.Journal of biomedical optics · 2018Article
- High-speed single-shot optical focusing through dynamic scattering media with full-phase wavefront shaping.Applied physics letters · 2017Article
- Focusing light through scattering media by polarization modulation based generalized digital optical phase conjugation.Applied physics letters · 2017Article
- Focusing light inside dynamic scattering media with millisecond digital optical phase conjugation.Optica · 2017Article
- Article
- Focusing light through biological tissue and tissue-mimicking phantoms up to 9.6 cm in thickness with digital optical phase conjugation.Journal of biomedical optics · 2016Article
- Tutorial on photoacoustic tomography.Journal of biomedical optics · 2016Review
- Bit-efficient, sub-millisecond wavefront measurement using a lock-in camera for time-reversal based optical focusing inside scattering media.Optics letters · 2016Article
- Focusing light through scattering media by full-polarization digital optical phase conjugation.Optics letters · 2016Article
- Seeing Through the Surface: Non-invasive Characterization of Biomaterial-Tissue Interactions Using Photoacoustic Microscopy.Annals of biomedical engineering · 2016Review
- Single-exposure optical focusing inside scattering media using binarized time-reversed adapted perturbation.Optica · 2015Article
- Super-resolution photoacoustic imaging through a scattering wall.Nature communications · 2015Article
- Optical-resolution photoacoustic endomicroscopy in vivo.Biomedical optics express · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The imaging depth of ballistic optical imaging technologies is limited by light scattering. To study the effects of scattering on optical-resolution photoacoustic microscopy (OR-PAM), the signals were divided into target and background signals. A method to simulate the point spread function (PSF) of the PAM system considering both optical illumination and acoustic detection was proposed, then the PSF was used to calculate the contribution of each class of signal at different depths of the focal plane (zf). How image contrast is degraded when there is a uniformly absorbing background as well as when there are small targets densely packed in the acoustic resolution cell were studied. By using the hyperboloid-focusing-based Monte Carlo method, optical focusing into a scattering medium was simulated. It was found that the lateral resolution provided by optical focusing is degraded by only 14% when zf=1.1 transport mean free path (l t'), compared with the case of no scattering. When zf=1.7 lt', the fluence at 50 μm radial distance away from the focal point is 93% of that at the focal point, which shows optical focusing is very weak at this depth. The method to simulate the PSF of PAM can be used in the future to optimize parameters so as to improve the system performance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.