ArticleNature communications2012
Distinct modes of DNA accessibility in plant chromatin.
Article in Nature communications, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 62 citations in OpenAlex.
- A side-by-side comparison of commercial CUT&RUN kits.Journal of biomolecular techniques : JBT · 2026Article
- The histone variant H3.14 is an early player in the abiotic stress response of Arabidopsis.Developmental cell · 2025Article
- The chromatin accessibility landscape during early maize seed development.The Plant journal : for cell and molecular biology · 2025Article
- The histone demethylase JMJ27 acts during the UV-induced modulation of H3K9me2 landscape and facilitates photodamage repair.Nature plants · 2024Article
- Non-CG DNA hypomethylation promotes photosynthesis and nitrogen fixation in soybean.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Forces driving transposable element load variation during Arabidopsis range expansion.The Plant cell · 2024Article
- Canalization of genome-wide transcriptional activity in Arabidopsis thaliana accessions by MET1-dependent CG methylation.Genome biology · 2022Article
- Asymmetric subgenomic chromatin architecture impacts on gene expression in resynthesized and natural allopolyploid Brassica napus.Communications biology · 2022Article
- Article
- H2AK121ub in Arabidopsis associates with a less accessible chromatin state at transcriptional regulation hotspots.Nature communications · 2021Article
- Epigenetic regulation of spurious transcription initiation in Arabidopsis.Nature communications · 2020Article
- The EC-HDA9 complex rhythmically regulates histone acetylation at theCommunications biology · 2019Article
- A tribute to Lars Hennig (1970-2018).Journal of experimental botany · 2018Article
- Auxin: a molecular trigger of seed development.Genes & development · 2018Review
- Emerging roles of chromatin in the maintenance of genome organization and function in plants.Genome biology · 2017Review
- Genome architecture: from linear organisation of chromatin to the 3D assembly in the nucleus.Chromosoma · 2016Review
- H3K36ac Is an Evolutionary Conserved Plant Histone Modification That Marks Active Genes.Plant physiology · 2016Article
- Arabidopsis Motif Scanner.BMC bioinformatics · 2016Article
- Review
- Structure and Function of Centromeric and Pericentromeric Heterochromatin in Arabidopsis thaliana.Frontiers in plant science · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The accessibility of DNA to regulatory proteins is a major property of the chromatin environment that favours or hinders transcription. Recent studies in flies reported that H3K9me2-marked heterochromatin is accessible while H3K27me3-marked chromatin forms extensive domains of low accessibility. Here we show that plants regulate DNA accessibility differently. H3K9me2-marked heterochromatin is the least accessible in the Arabidopsis thaliana genome, and H3K27me3-marked chromatin also has low accessibility. We see that very long genes without H3K9me2 or H3K27me3 are often inaccessible and generated significantly lower amounts of antisense transcripts than other genes, suggesting that reduced accessibility is associated with reduced recognition of alternative promoters. Low accessibility of H3K9me2-marked heterochromatin and long genes depend on cytosine methylation, explaining why chromatin accessibility differs between plants and flies. Together, we conclude that restriction of DNA accessibility is a local property of chromatin and not necessarily a consequence of microscopically visible compaction.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.