ArticleCritical care medicine2013
Quality of life before intensive care using EQ-5D: patient versus proxy responses.
Article in Critical care medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Quality of life in elderly ICU survivors before the COVID-19 pandemic: a systematic review and meta-analysis of cohort studies.BMJ open · 2021Pooled it
- Feasibility and reliability of frailty assessment in the critically ill: a systematic review.Critical care (London, England) · 2018Pooled it
- Health-related quality-of-life among survivors of acute kidney injury in the intensive care unit: a systematic review.Intensive care medicine · 2016Pooled it
- Predictors of 6-month health utility outcomes in survivors of acute respiratory distress syndrome.Thorax · 2017Trial
- Impaired Pre-Critical Illness Quality of Life in Elderly ICU Patients.Acta anaesthesiologica Scandinavica · 2026Observational
- Elder abuse and the association with ear or hearing diseases in advanced age: a cross-sectional study.BMC geriatrics · 2026Article
- An Early-Stage Decision-Analytic Health Economic Model of Above Cuff Vocalization: What Do We Know and What Do We Need to Resolve?Critical care explorations · 2025Article
- Identifying distinct clusters of ICU survivors by integrating demographic, pre-admission quality of life, and clinical data: a large prospective cohort study.Intensive care medicine · 2025Article
- Reliability of pre-admission patient-reported outcome measures postoperatively assessed via proxies: a prospective, multicenter observational study.Critical care (London, England) · 2025Observational
- Health-Related Quality of Life Among Patients Who Have Survived an Episode of Sepsis in the United States: A Systematic Review.Infectious diseases and therapy · 2025Review
- Observational
- Changes in quality of life 1 year after intensive care: a multicenter prospective cohort of ICU survivors.Critical care (London, England) · 2024Article
- Is comorbidity alone responsible for changes in health-related quality of life among critical care survivors? A purpose-specific review.Critical care (London, England) · 2024Review
- Pre-Burn Health-Related Quality of Life: Patient and Partner Perspectives.European burn journal · 2022Article
- EQ-5D-5L in Schizophrenia: differences between patients and nurses' reports.Health and quality of life outcomes · 2021Article
- The impact of sarcopenia and acute muscle mass loss on long-term outcomes in critically ill patients with intra-abdominal sepsis.Journal of cachexia, sarcopenia and muscle · 2021Article
- Chronic Critical Illness Patients Fail to Respond to Current Evidence-Based Intensive Care Nutrition Secondarily to Persistent Inflammation, Immunosuppression, and Catabolic Syndrome.JPEN. Journal of parenteral and enteral nutrition · 2020Article
- Physical, Mental, and Cognitive Health Status of ICU Survivors Before ICU Admission: A Cohort Study.Critical care medicine · 2020Article
- Assessing the proxy response bias of EQ-5D-3 L in general population: a study based on a large-scale representative household health survey using propensity score matching.Health and quality of life outcomes · 2020Article
- Participating in core outcome set development via Delphi surveys: qualitative interviews provide pointers to inform guidance.BMJ open · 2019Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
objectiveTo compare patients' retrospectively reported baseline quality of life before intensive care hospitalization with population norms and proxy reports.
designProspective cohort study.
settingThirteen ICUs at four teaching hospitals in Baltimore, MD. PATIENTS: One hundred forty acute lung injury survivors and their designated proxies.
interventionsAround the time of hospital discharge, both patients and proxies were asked to retrospectively estimate patients' baseline quality of life before hospital admission using the EQ-5D quality-of-life instrument. MEASUREMENTS AND MAIN
resultsMean patient-rated EQ-5D visual analog scale scores and utility scores were significantly lower than population norms but were significantly higher than proxy ratings. However, the magnitude of difference in average utility scores between patients and either population norms or proxies was not clinically important. For the five individual EQ-5D domains, κ statistics revealed slight to fair agreement between patients and proxies. Bland-Altman plots demonstrated that for both the visual analog scale and utility scores, proxies underestimated scores when patients reported high ratings and overestimated scores for low patient ratings.
conclusionsPatients retrospectively reported worse baseline health status before acute lung injury than population norms and better status than proxy reports; however, the magnitude of these differences in health status may not be clinically important. Proxies had only slight to fair agreement with patients in all five EQ-5D domains, attenuating patients' more extreme ratings toward moderate scores. Caution is required when interpreting proxy retrospective reports of baseline health status for survivors of acute lung injury.
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