ArticleParasites & vectors2012
New species of Ehrlichia isolated from Rhipicephalus (Boophilus) microplus shows an ortholog of the E. canis major immunogenic glycoprotein gp36 with a new sequence of tandem repeats.
Article in Parasites & vectors, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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25 citing papers in PubMed.
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- Metagenome reveals the midgut microbial community of Haemaphysalis qinghaiensis ticks collected from yaks and Tibetan sheep.Parasites & vectors · 2024Article
- Molecular diagnosis and characterization of Anaplasma marginale and Ehrlichia ruminantium infecting beef cattle of Maputo Province, Mozambique.BMC veterinary research · 2024Article
- Pathogenic Rickettsia, Anaplasma, and Ehrlichia in Rhipicephalus microplus ticks collected from cattle and laboratory hatched tick larvae.PLoS neglected tropical diseases · 2023Article
- Diversity of Rickettsiales bacteria in five species of ticks collected from Jinzhai County, Anhui Province, China in 2021-2022.Frontiers in microbiology · 2023Article
- Molecular prevalence and risk factors associated with tick-borne pathogens in cattle in western Kenya.BMC veterinary research · 2021Article
- Bacterial Pathogens and Symbionts Harboured byPathogens (Basel, Switzerland) · 2021Article
- First Evidence ofPathogens (Basel, Switzerland) · 2021Article
- Diversity unearthed by the estimated molecular phylogeny and ecologically quantitative characteristics of uncultured Ehrlichia bacteria in Haemaphysalis ticks, Japan.Scientific reports · 2021Article
- Comparative Analysis of Genome of Ehrlichia sp. HF, a Model Bacterium to Study Fatal Human Ehrlichiosis.BMC genomics · 2021Article
- Molecular Prevalence ofFrontiers in veterinary science · 2021Article
- Molecular screening of Anaplasmataceae in ticks collected from cattle in Corsica, France.Experimental & applied acarology · 2020Article
- Isolation and Characterization of a Novel Pathogenic Strain ofMicroorganisms · 2019Article
- Emergence of a NovelMicroorganisms · 2019Article
- Complete Genome Sequence of anMicrobiology resource announcements · 2019Article
- Ticks, rickettsial and erlichial infection in small mammals from Atlantic forest remnants in northeastern Brazil.International journal for parasitology. Parasites and wildlife · 2018Article
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8 authors.
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Abstract
backgroundEhrlichia species are the etiological agents of emerging and life-threatening tick-borne human zoonoses that inflict serious and fatal infections in companion animals and livestock. The aim of this paper was to phylogeneticaly characterise a new species of Ehrlichia isolated from Rhipicephalus (Boophilus) microplus from Minas Gerais, Brazil.
methodsThe agent was isolated from the hemolymph of Rhipicephalus (B.) microplus engorged females that had been collected from naturally infested cattle in a farm in the state of Minas Gerais, Brazil. This agent was then established and cultured in IDE8 tick cells. The molecular and phylogenetic analysis was based on 16S rRNA, groEL, dsb, gltA and gp36 genes. We used the maximum likelihood method to construct the phylogenetic trees.
resultsThe phylogenetic trees based on 16S rRNA, groEL, dsb and gltA showed that the Ehrlichia spp isolated in this study falls in a clade separated from any previously reported Ehrlichia spp. The molecular analysis of the ortholog of gp36, the major immunoreactive glycoproteins in E. canis and ortholog of the E. chaffeensis gp47, showed a unique tandem repeat of 9 amino acids (VPAASGDAQ) when compared with those reported for E. canis, E. chaffeensis and the related mucin-like protein in E. ruminantium.
conclusionsBased on the molecular and phylogenetic analysis of the 16S rRNA, groEL, dsb and gltA genes we concluded that this tick-derived microorganism isolated in Brazil is a new species, named E. mineirensis (UFMG-EV), with predicted novel antigenic properties in the gp36 ortholog glycoprotein. Further studies on this new Ehrlichia spp should address questions about its transmissibility by ticks and its pathogenicity for mammalian hosts.
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