ArticleBMC infectious diseases2012
Household transmission of respiratory viruses - assessment of viral, individual and household characteristics in a population study of healthy Australian adults.
Article in BMC infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 19 citations in OpenAlex.
- Role-specific household contact patterns in urban and rural China: Implications for influenza household transmission.Infectious Disease Modelling · 2027Article
- Article
- Impact of Nonpharmacological Interventions on Severe Acute Respiratory Infections in Children: From the National Surveillance Database.Journal of Korean medical science · 2023Article
- Household transmission of influenza A and B within a prospective cohort during the 2013-2014 and 2014-2015 seasons.Statistics in medicine · 2021Article
- Household presentation of influenza and acute respiratory illnesses to a primary care sentinel network: retrospective database studies (2013-2018).BMC public health · 2020Article
- Influenza-like illness in Australia: A comparison of general practice surveillance system with electronic medical records.Influenza and other respiratory viruses · 2020Article
- Risk factors and patterns of household clusters of respiratory viruses in rural Nepal.Epidemiology and infection · 2019Article
- Transmission of respiratory and gastrointestinal infections in German households with children attending child care.Epidemiology and infection · 2018Article
- Transmission of rhinovirus in the Utah BIG-LoVE families: Consequences of age and household structure.PloS one · 2018Article
- Epidemiology and etiology of influenza-like-illness in households in Vietnam; it's not all about the kids!Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2016Article
- Social encounter profiles of greater Melbourne residents, by location--a telephone survey.BMC infectious diseases · 2015Article
- Factors associated with transmission of influenza-like illness in a cohort of households containing multiple children.Influenza and other respiratory viruses · 2015Article
- The French Connection: The First Large Population-Based Contact Survey in France Relevant for the Spread of Infectious Diseases.PloS one · 2015Article
- Incidence and risk factors for influenza-like-illness in the UK: online surveillance using Flusurvey.BMC infectious diseases · 2014Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHousehold transmission of influenza-like illness (ILI) may vary with viral and demographic characteristics. We examined the effect of these factors in a population-based sample of adults with ILI.
methodsWe conducted a prospective cohort study in community-dwelling Australian adults nested within an influenza vaccine effectiveness trial. On presentation with ILI, participants were swabbed for a range of respiratory viruses and asked to return a questionnaire collecting details of household members with or without similar symptoms. We used logistic and Poisson regression to assess the key characteristics of household transmission.
results258 participants from multi-occupancy households experienced 279 ILI episodes and returned a questionnaire. Of these, 183 were the primary case in the household allowing assessment of factors associated with transmission. Transmission was significantly associated in univariate analyses with female sex (27% vs. 13%, risk ratio (RR) = 2.13 (1.08, 4.21)) and the presence of a child in the house (33% vs. 17%, RR = 1.90 (1.11, 3.26)). The secondary household attack proportion (SHAP) was 0.14, higher if influenza was isolated (RR = 2.1 (1.0, 4.5)). Vaccinated participants who nonetheless became infected with influenza had a higher SHAP (Incidence RR = 5.24 (2.17, 12.6)).
conclusionsThe increased SHAP in households of vaccinated participants who nonetheless had confirmed influenza infection supports the hypothesis that in years of vaccine mismatch, not only is influenza vaccine less protective for the vaccine recipient, but that the population's immunity is also lower.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.