ArticleChemical communications (Cambridge, England)2013
Artificial repressors for controlling gene expression in bacteria.
Article in Chemical communications (Cambridge, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 43 citations in OpenAlex.
- Synthetic Biology of Plants and Microbes for Agriculture, Environment, and Future Applications.Chemical reviews · 2026Review
- When push comes to shove - RNA polymerase and DNA-bound protein roadblocks.Biophysical reviews · 2023Review
- Growth-coupled bioconversion of levulinic acid to butanone.Metabolic engineering · 2019Article
- Exploring of the feature space of de novo developed post-transcriptional riboregulators.PLoS computational biology · 2018Article
- Selective recognition ofPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Article
- Distinct and redundant functions of three homologs of RNase III in the cyanobacterium Synechococcus sp. strain PCC 7002.Nucleic acids research · 2018Article
- Transcription control engineering and applications in synthetic biology.Synthetic and systems biotechnology · 2017Review
- The effect of increasing numbers of repeats on TAL effector DNA binding specificity.Nucleic acids research · 2017Article
- Exploiting the sequence diversity of TALE-like repeats to vary the strength of dTALE-promoter interactions.Synthetic biology (Oxford, England) · 2017Article
- A transcription activator-like effector (TALE) induction system mediated by proteolysis.Nature chemical biology · 2016Article
- DNA-binding proteins from marine bacteria expand the known sequence diversity of TALE-like repeats.Nucleic acids research · 2015Article
- Control of Gene Expression in Leptospira spp. by Transcription Activator-Like Effectors Demonstrates a Potential Role for LigA and LigB in Leptospira interrogans Virulence.Applied and environmental microbiology · 2015Article
- RiboTALE: A modular, inducible system for accurate gene expression control.Scientific reports · 2015Article
- TAL effectors and activation of predicted host targets distinguish Asian from African strains of the rice pathogen Xanthomonas oryzae pv. oryzicola while strict conservation suggests universal importance of five TAL effectors.Frontiers in plant science · 2015Article
- Modes of TAL effector-mediated repression.Nucleic acids research · 2014Article
- Regulation of endogenous human gene expression by ligand-inducible TALE transcription factors.ACS synthetic biology · 2014Article
- Transcription activator-like effectors: a toolkit for synthetic biology.ACS synthetic biology · 2014Review
- Application of TALEs, CRISPR/Cas and sRNAs as trans-acting regulators in prokaryotes.Current opinion in biotechnology · 2014Review
- Principles and applications of TAL effectors for plant physiology and metabolism.Current opinion in plant biology · 2014Article
- Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Transcriptional repression is a common approach to control gene expression in synthetic biology applications. Here, an engineered DNA binding protein based upon a transcription activator-like effector (TALE) scaffold was shown to outperform LacI in blocking transcription from a promoter and to repress expression of a downstream gene in an operon.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.