ArticleJournal of vascular and interventional neurology2012
Recruitment and retention monitoring: facilitating the mission of the National Institute of Neurological Disorders and Stroke (NINDS).
Article in Journal of vascular and interventional neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Barriers and facilitators for recruiting and retaining male participants into longitudinal health research: a systematic review.BMC medical research methodology · 2024Pooled it
- Trial
- Trial
- Understanding Barriers and Facilitators for Ethnic Minority Groups to Audio Recording Recruitment Discussions in Clinical Trials: A Participatory Approach to Improving Informed Consent and Participation.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- Article
- Clinical trial site identification practices and the use of electronic health records in feasibility evaluations: An interview study in the Nordic countries.Clinical trials (London, England) · 2021Article
- Strategies for Behavioral Research in Neurology: Lessons Learned During the COVID-19 Pandemic and Applications for the Future.Current neurology and neuroscience reports · 2021Review
- Examining recruitment feasibility and related outcomes in adults post-stroke.Pilot and feasibility studies · 2020Article
- Time- and Race-Specific Haematological Reference Intervals for Healthy Volunteer Trials: A Retrospective Analysis of Pooled Data From Multiple Phase I Trials.Frontiers in pharmacology · 2020Article
- Ethics and Bias in Clinical Trial Enrollment in Stroke.Current cardiology reports · 2019Review
- Barriers and Strategies for Recruitment of Racial and Ethnic Minorities: Perspectives from Neurological Clinical Research Coordinators.Journal of racial and ethnic health disparities · 2017Article
- Overcoming practical challenges to conducting clinical research in the inpatient stroke rehabilitation setting.Topics in stroke rehabilitation · 2015Article
- Examining Barriers and Practices to Recruitment and Retention in Stroke Clinical Trials.Stroke · 2015Article
- Engaging veterans with substance abuse disorders into a research trial: success with study branding, networking, and presence.Translational behavioral medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is commonly accepted that inefficient recruitment and inadequate retention continue to threaten the completion of clinical trials intended to reduce the public health burden of neurological disease. This article will discuss the scientific, economic, and ethical implications of failure to recruit and retain adequate samples in clinical trials, including the consequences of failing to recruit adequately diverse samples. We will also discuss the more common challenges and barriers to efficient and effective recruitment and retention, and the impact these have on successful clinical trial planning. We will explain the newly established efforts within National Institute of Neurological Disorders and Stroke (NINDS) to monitor recruitment and retention with well-defined metrics and implementation of grant awards that include feasibility milestones for continued funding. Finally, we will describe our efforts to address some of the common challenges to recruitment and retention through assistance to investigators and coordinators with evidence-based support, tools, and resources for planning and strategizing recruitment and retention as well as a trans-NIH effort to improve awareness of clinical research in the general public.
Identifiers
23230460PMC3517027What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.