Evidence map›Paper›PMID 23229649›Full record

ReviewJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2013

Regadenoson: a focused update.

Gopal Ghimire, Fadi G Hage, Jaekyeong Heo, Ami E Iskandrian

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Incidence of atrioventricular block with vasodilator stress SPECT: A meta-analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Pooled it
  2. Safety and tolerability of intravenous regadenoson in healthy subjects: A randomized, repeat-dose, placebo-controlled study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Trial
  3. Article
  4. Review
  5. Review
  6. Prognostic value of absent left ventricular ejection fraction reserve with regadenoson SPECT MPI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  7. Article
  8. Agonist-Dependent Coupling of the Promiscuous Adenosine AACS pharmacology & translational science · 2022
    Article
  9. Review
  10. Review
  11. Safer stress tests for myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  12. Myocardial CT perfusion imaging for ischemia detection.Cardiovascular diagnosis and therapy · 2017
    Review
  13. A helping hand for regadenoson tests.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  14. Prognostic value of transient ischemic dilation with regadenoson myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016
    Article
  15. Immortality time and serial myocardial perfusion imaging: Only those who do not die may repeat the exam.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016
    Article
  16. The prognostic value of regadenoson myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015
    Article
  17. Serious and potentially life threatening complications of cardiac stress testing: Physiological mechanisms and management strategies.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015
    Review
  18. Quantification of myocardial perfusion in clinical trials.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015
    Article
  19. Review
  20. Regadenoson use in patients with chronic obstructive pulmonary disease: the state of current knowledge.International journal of chronic obstructive pulmonary disease · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gopal GhimireDivision of Cardiovascular Diseases, University of Alabama at Birmingham, 318 LHRH, 1900, University Blvd, Birmingham, AL 35294, USA.
Fadi G Hage
Jaekyeong Heo
Ami E Iskandrian

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since its approval by the Food and Drug Administration in 2008, regadenoson has become the most commonly used vasodilator in the United States. Previous reviews have summarized the pre-clinical and clinical data on the use of regadenoson for myocardial perfusion imaging (MPI). Since then, data have emerged on the safety of this agent in special groups of patients such as those with chronic kidney disease, airway disease (asthma and chronic obstructive pulmonary disease), and liver disease. There has also been recent interest in the use of regadenoson in hybrid protocols with exercise as a way to improve patient tolerance and image quality. Finally, although regadenoson was approved for clinical use based on the agreement rate of regadenoson MPI and adenosine MPI with regards to perfusion abnormalities, data are now available on the prognostic data derived from regadenoson MPI. We will briefly summarize these recent reports here in a focused update on the use of regadenoson for MPI.

Indexed as

Coronary Artery DiseaseEvidence-Based MedicineExercise TestHumansMyocardial Perfusion ImagingPurinesPyrazolesReproducibility of ResultsSensitivity and SpecificityTomography, Emission-Computed, Single-PhotonVasodilator AgentsPurinesPyrazolesregadenosonVasodilator Agents

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.