ArticleBMC genomics2012
The genome of Pelobacter carbinolicus reveals surprising metabolic capabilities and physiological features.
Article in BMC genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 37 citations in OpenAlex.
- Exploring Trimethylaminuria: Genetics and Molecular Mechanisms, Epidemiology, and Emerging Therapeutic Strategies.Biology · 2024Review
- Energetically exploiting lignocellulose-rich residues in anaerobic digestion technologies: from bioreactors to proteogenomics.Biotechnology for biofuels and bioproducts · 2023Article
- Interspecies Formate Exchange Drives Syntrophic Growth ofApplied and environmental microbiology · 2022Article
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- Shift of DNRA bacterial community composition in sediment cores of the Pearl River Estuary and the impact of environmental factors.Ecotoxicology (London, England) · 2021Article
- Simultaneous Genome Sequencing ofMicroorganisms · 2020Article
- Anaerobic degradation of hexadecane and phenanthrene coupled to sulfate reduction by enriched consortia from northern Gulf of Mexico seafloor sediment.Scientific reports · 2019Article
- Deltaproteobacteria (Pelobacter) and Methanococcoides are responsible for choline-dependent methanogenesis in a coastal saltmarsh sediment.The ISME journal · 2019Article
- Methodological considerations for the identification of choline and carnitine-degrading bacteria in the gut.Methods (San Diego, Calif.) · 2018Review
- Jellyfish Life Stages Shape Associated Microbial Communities, While a Core Microbiome Is Maintained Across All.Frontiers in microbiology · 2018Article
- Acetylene Fuels TCE Reductive Dechlorination by Defined Dehalococcoides/Pelobacter Consortia.Environmental science & technology · 2017Article
- Drivers of the dynamics of diazotrophs and denitrifiers in North Sea bottom waters and sediments.Frontiers in microbiology · 2015Article
- Constraint-based modeling of carbon fixation and the energetics of electron transfer in Geobacter metallireducens.PLoS computational biology · 2014Article
- The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of Pathway/Genome Databases.Nucleic acids research · 2014Article
- Degradation of acetaldehyde and its precursors by Pelobacter carbinolicus and P. acetylenicus.PloS one · 2014Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe bacterium Pelobacter carbinolicus is able to grow by fermentation, syntrophic hydrogen/formate transfer, or electron transfer to sulfur from short-chain alcohols, hydrogen or formate; it does not oxidize acetate and is not known to ferment any sugars or grow autotrophically. The genome of P. carbinolicus was sequenced in order to understand its metabolic capabilities and physiological features in comparison with its relatives, acetate-oxidizing Geobacter species.
resultsPathways were predicted for catabolism of known substrates: 2,3-butanediol, acetoin, glycerol, 1,2-ethanediol, ethanolamine, choline and ethanol. Multiple isozymes of 2,3-butanediol dehydrogenase, ATP synthase and [FeFe]-hydrogenase were differentiated and assigned roles according to their structural properties and genomic contexts. The absence of asparagine synthetase and the presence of a mutant tRNA for asparagine encoded among RNA-active enzymes suggest that P. carbinolicus may make asparaginyl-tRNA in a novel way. Catabolic glutamate dehydrogenases were discovered, implying that the tricarboxylic acid (TCA) cycle can function catabolically. A phosphotransferase system for uptake of sugars was discovered, along with enzymes that function in 2,3-butanediol production. Pyruvate:ferredoxin/flavodoxin oxidoreductase was identified as a potential bottleneck in both the supply of oxaloacetate for oxidation of acetate by the TCA cycle and the connection of glycolysis to production of ethanol. The P. carbinolicus genome was found to encode autotransporters and various appendages, including three proteins with similarity to the geopilin of electroconductive nanowires.
conclusionsSeveral surprising metabolic capabilities and physiological features were predicted from the genome of P. carbinolicus, suggesting that it is more versatile than anticipated.
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Registered trials
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