Evidence map›Paper›PMID 23227348›Full record

ArticleInternational journal of hepatology2012

Treatment of neuroendocrine tumor liver metastases.

Mark A Lewis, Timothy J Hobday

Open access · goldAbstract read
In one paragraph

Article in International journal of hepatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Cryotherapy for liver metastases.The Cochrane database of systematic reviews · 2019
    Pooled it
  2. Neuroendocrine liver metastasis.Hepatobiliary surgery and nutrition · 2025
    Article
  3. Article
  4. Article
  5. Comparison ofCurrent oncology (Toronto, Ont.) · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Evaluation and Management of Neuroendocrine Tumors of the Pancreas.The Surgical clinics of North America · 2019
    Review
  12. Evidence-Based Policy in Practice: Management of Carcinoid Syndrome Diarrhea.P & T : a peer-reviewed journal for formulary management · 2019
    Article
  13. Review
  14. Article
  15. Review
  16. Liver Ablation: Best Practice.Radiologic clinics of North America · 2015
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mark A LewisDivision of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Timothy J Hobday
Mayo Clinic in Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the care of patients with hepatic neuroendocrine metastases, medical oncologists should work in multidisciplinary fashion with surgeons, interventional radiologists, and radiation oncologists to assess the potential utility of liver-directed and systemic therapies. This paper addresses the various roles and evidence basis for cytoreductive surgery, thermal ablation (radiofrequency, microwave, and cryoablation), and embolization (bland embolization (HAE), chemoembolization (HACE), and radioembolization) as liver-directed therapies. Somatostatin analogues, cytotoxic chemotherapy, and the newer agents everolimus and suntinib are discussed as a means for controlling intra- and extrahepatic disease, along with peptide receptor radiotherapy (PRRT). Finally, the experience with orthotopic liver transplant for neuroendocrine tumors is described.

Identifiers

PMID23227348
PMCPMC3512291
OpenAlexW2020377338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.