ArticleInternational journal of breast cancer2012
Age at diagnosis and breast cancer survival in iran.
Article in International journal of breast cancer, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The trial behind it
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Who cites it
21 citing papers in PubMed, 47 citations in OpenAlex.
- Trial
- Breast cancer care for the aging population: a focus on age-related disparities in breast cancer treatment.BMC cancer · 2025Article
- Mortality Rate and Years of Life Lost Due to Breast and Gynecologic Cancers in Southern Iran 2004-2019: A Population-Based Study.Iranian journal of public health · 2024Article
- Prognostic Factors Associated with Breast Cancer-Specific Survival from 1995 to 2022: A Systematic Review and Meta-Analysis of 1,386,663 Cases from 30 Countries.Diseases (Basel, Switzerland) · 2024Review
- Does age affect outcome with breast cancer?Breast (Edinburgh, Scotland) · 2023Article
- Time-related survival prediction in molecular subtypes of breast cancer using time-to-event deep-learning-based models.Frontiers in oncology · 2023Article
- Age at Diagnosis of Breast Cancer in Iran: A Systematic Review and Meta-Analysis.Iranian journal of public health · 2021Review
- Clinicopathological characteristics of young versus older patients with breast cancer: A retrospective comparative study from the Madinah region of Saudi Arabia.Saudi medical journal · 2021Article
- Article
- Cost analysis of breast cancer: a comparison between private and public hospitals in Iran.BMC health services research · 2021Article
- Determination of the Risk Factors for Breast Cancer Survival using the Bayesian Method, Yazd, Iran.Advanced biomedical research · 2021Article
- Prognostic factors influencing prognosis in early breast cancer patients.Przeglad menopauzalny = Menopause review · 2019Article
- Expression Analysis of MALAT1, GAS5, SRA, and NEAT1 lncRNAs in Breast Cancer Tissues from Young Women and Women over 45 Years of Age.Molecular therapy. Nucleic acids · 2018Article
- Do site and type of metastasis in breast cancer show a changing pattern with increased age? A cross comparison of clinicopathological characteristics between age groups.World journal of surgical oncology · 2018Article
- Adjuvant Trastuzumab Therapy for Early HER2-Positive Breast Cancer in Iran: A Cost-Effectiveness and Scenario Analysis for an Optimal Treatment Strategy.PharmacoEconomics · 2018Article
- Use of data-mining to support real-world cost analyses: An example using HER2-positive breast cancer in Iran.PloS one · 2018Article
- Metastasis and its Related Factors in Female Breast Cancer Patients in Kerman, IranAsian Pacific journal of cancer prevention : APJCP · 2017Article
- Cost-Effectiveness of Three Rounds of Mammography Breast Cancer Screening in Iranian Women.Iranian journal of cancer prevention · 2016Article
- Effect of Age on Breast Cancer Patient Prognoses: A Population-Based Study Using the SEER 18 Database.PloS one · 2016Article
- The Economic Burden of Breast Cancer in Iran.Iranian journal of public health · 2015Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. Tumour characteristics are the most important prognostic factors in breast cancer. Patient-related factors such as young age at diagnosis, obesity, and smoking behaviour may also modify disease outcome. Due to the absence of a unique definition for "young age breast cancer" and the resulting variation in disease management, findings on the association between young age and prognosis of breast cancer are controversial. Methods. This study included 1500 patients with a primary diagnosis of breast cancer in six Iranian hospitals from 5 provinces. We modelled the relative excess risk (RER) of breast cancer death to age at diagnosis and tumour characteristics. Results. Excess risks of death were observed for stage IV disease and poorly differentiated tumours: RER of 4.3 (95% CI: 1.05-17.65) and 3.4 (95% CI: 1.17-9.87), respectively. "Older" patients, particularly those aged 50 and over, presented more often with advanced and poorly differentiated tumours (P = 0.001). After adjustment for stage, histological grade, Her-2 expression, estrogen and progesterone receptors, and place of residency, breast cancer mortality was not significantly different across age groups. Conclusion. We conclude that there is no prognostic effect of age at diagnosis of breast cancer among breast cancer patients treated at cancer centres in different parts of Iran; young and relatively old women have similar risks of dying from breast cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.