ArticlePloS one2012
U-shaped relation between plasma oxytocin levels and behavior in the trust game.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Article
- Intranasal oxytocin does not change partner preference in female titi monkeys (Plecturocebus cupreus), but intranasal vasopressin decreases it.Journal of neuroendocrinology · 2023Article
- Temporal Dynamics of Intranasal Oxytocin in Human Brain Electrophysiology.Cerebral cortex (New York, N.Y. : 1991) · 2022Review
- Is oxytocin a trust hormone? Salivary oxytocin is associated with caution but not with general trust.PloS one · 2022Article
- The Effects of Oxytocin on Appetite Regulation, Food Intake and Metabolism in Humans.International journal of molecular sciences · 2021Review
- Improving the precision of intranasal oxytocin research.Nature human behaviour · 2021Review
- Central oxytocin signaling inhibits food reward-motivated behaviors and VTA dopamine responses to food-predictive cues in male rats.Hormones and behavior · 2020Article
- Cortisol, oxytocin, and quality of life in major depressive disorder.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Article
- LeuScientific reports · 2019Article
- Connectome-based model predicts individual differences in propensity to trust.Human brain mapping · 2019Article
- Trust Games and Beyond.Frontiers in neuroscience · 2019Review
- Oxytocin Facilitates Social Learning by Promoting Conformity to Trusted Individuals.Frontiers in neuroscience · 2019Review
- Association of the oxytocin receptor gene with attitudinal trust: role of amygdala volume.Social cognitive and affective neuroscience · 2018Article
- Endogenous oxytocin predicts helping and conversation as a function of group membership.Proceedings. Biological sciences · 2018Article
- The (Null) Effect of Affective Touch on Betrayal Aversion, Altruism, and Risk Taking.Frontiers in behavioral neuroscience · 2017Article
- Risk and resistance perspectives in translation-oriented etiology research.Translational behavioral medicine · 2016Review
- Vasopressin and oxytocin receptor systems in the brain: Sex differences and sex-specific regulation of social behavior.Frontiers in neuroendocrinology · 2016Review
- Lower Oxytocin Plasma Levels in Borderline Patients with Unresolved Attachment Representations.Frontiers in human neuroscience · 2016Article
- Association between the dopamine D4 receptor gene exon III variable number of tandem repeats and political attitudes in female Han Chinese.Proceedings. Biological sciences · 2015Article
- Genomic conflicts and sexual antagonism in human health: insights from oxytocin and testosterone.Evolutionary applications · 2015Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trust underpins much of social and economic exchanges across human societies. In experimental economics, the Trust Game has served as the workhorse for the study of trust in a controlled incentivized setting. Recent evidence using intranasal drug administration, aka 'sniffing', suggests that oxytocin (OT) can function as a social hormone facilitating trust and other affiliative behaviors. Here we hypothesized that baseline plasma OT is a biomarker that partially predicts the degree of trust and trustworthiness observed in the trust game. Using a large sample of 1,158 participants, we observed a significant U-shaped relationship between plasma OT with the level of trust, and marginally with the level of trustworthiness, especially among males. Specifically, subjects with more extreme levels of plasma OT were more likely to be trusting as well as trustworthy than those with moderate levels of plasma OT. Our results contribute to a deeper understanding of the biological basis of human trust and underscore the usefulness of peripheral plasma OT measures in characterizing human social behavior.
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