Evidence map›Paper›PMID 23227121›Full record

ReviewTheranostics2012

Image guided biodistribution and pharmacokinetic studies of theranostics.

Hong Ding, Fang Wu

Abstract readReview
In one paragraph

Review in Theranostics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

  1. Fluorinated Amphiphilic Dendrimer to Improve PET Imaging of Cancer.Small (Weinheim an der Bergstrasse, Germany) · 2026
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  6. Preclinical Evaluation Study ofChemical & biomedical imaging · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Biomedical Approach of Nanotechnology and Biological Risks: A Mini-Review.International journal of molecular sciences · 2023
    Review
  16. Review
  17. Article
  18. Functionalization of and through Melanin: Strategies and Bio-Applications.International journal of molecular sciences · 2023
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hong DingDepartment of Immunology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA. hding@fiu.edu
Fang Wu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Image guided technique is playing an increasingly important role in the investigation of the biodistribution and pharmacokinetics of drugs or drug delivery systems in various diseases, especially cancers. Besides anatomical imaging modalities such as computed tomography (CT), magnetic resonance imaging (MRI), molecular imaging strategy including optical imaging, positron emission tomography (PET) and single-photon emission computed tomography (SPECT) will facilitate the localization and quantization of radioisotope or optical probe labeled nanoparticle delivery systems in the category of theranostics. The quantitative measurement of the bio-distribution and pharmacokinetics of theranostics in the fields of new drug/probe development, diagnosis and treatment process monitoring as well as tracking the brain-blood-barrier (BBB) breaking through by high sensitive imaging method, and the applications of the representative imaging modalities are summarized in this review.

Indexed as

PharmacokineticsAnimalsBlood-Brain BarrierDiagnostic ImagingHumansNanoparticlesOptical ImagingTissue Distributionantibody.biodistributionImagenanoparticlespharmacokinetictheranostics

Identifiers

PMID23227121
PMCPMC3516836

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.