Evidence map›Paper›PMID 23227089›Full record

ArticleClinical & developmental immunology2012

Association of autoantibodies to BP180 with disease activity in Greek patients with bullous pemphigoid.

Aikaterini Patsatsi, Aikaterini Kyriakou, Aikaterini Pavlitou-Tsiontsi, Anastasia Giannakou, Dimitrios Sotiriadis

Abstract read
In one paragraph

Article in Clinical & developmental immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Peptide Epitopes of NC16A BP180 in the Diagnostics of Bullous Pemphigoid.JID innovations : skin science from molecules to population health · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aikaterini Patsatsi2nd Department of Dermatology and Venereology, Papageorgiou General Hospital, Aristotle University School of Medicine, Thessaloniki, Greece.
Aikaterini Kyriakou
Aikaterini Pavlitou-Tsiontsi
Anastasia Giannakou
Dimitrios Sotiriadis

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

39 bullous pemphigoid (BP) patients were studied to assess the clinical significance of anti-BP180 and anti-BP230 circulating autoantibodies of BP and correlate their titers with the clinical scores of the BP Disease Area Index (BPDAI) and the Autoimmune Bullous Skin Disorder Intensity Score (ABSIS) as well as with the intensity of pruritus measured by the BPDAI pruritus component. All parameters were evaluated by the time of diagnosis (baseline), month 3, and month 6. Titers of anti-BP180 autoantibodies were strongly correlated with BPDAI (r = 0.557, P value < 0.0001) and ABSIS (r = 0.570, P value < 0.0001) values, as well as with BPDAI component for the intensity of pruritus (rho = 0.530, P value = 0.001) at baseline. At month 3, titers of anti-BP180 autoantibodies were strongly correlated with BPDAI (rho = 0.626, P value = 0.000) and ABSIS (rho = 0.625, P value = 0.000) values, as well as with the BPDAI component for the intensity of pruritus (rho = 0.625, P value = 0.000). At month 6, titers of anti-BP180 autoantibodies were strongly correlated with BPDAI (rho = 0.527, P value = 0.001) and ABSIS (rho = 0.526, P value = 0.001) values, as well as with the BPDAI component for the intensity of pruritus (rho = 0.525, P value = 0.001). There was no statistically significant correlation between titers of anti-BP230 autoantibodies and the BPDAI, ABSIS, and BPDAI component for the intensity of pruritus at the same time points.

Indexed as

AdultAgedAged, 80 and overAutoantibodiesAutoantigensCarrier ProteinsCohort StudiesCollagen Type XVIICytoskeletal ProteinsDystoninFemaleFollow-Up StudiesGreeceHumansMaleMembrane GlycoproteinsAutoantibodiesAutoantigensCarrier ProteinsCollagen Type XVIICytoskeletal ProteinsDST protein, humanDystoninMembrane GlycoproteinsNerve Tissue ProteinsNon-Fibrillar Collagens

Identifiers

PMID23227089
PMCPMC3514843

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.