ArticleOncology letters2012
The plasticity and potential of leukemia cell lines to differentiate into dendritic cells.
Article in Oncology letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 15 citations in OpenAlex.
- A human Caco-2-based co-culture model of the inflamed intestinal mucosa for particle toxicity studies.In vitro models · 2023Article
- The Impact of Exosomes/Microvesicles Derived from Myeloid Dendritic Cells Cultured in the Presence of Calcitriol and Tacalcitol on Acute B-Cell Precursor Cell Lines withJournal of clinical medicine · 2022Article
- Establishing Preferred Product Characterization for the Evaluation of RNA Vaccine Antigens.Vaccines · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dendritic cells (DCs) are potent antigen-presenting cells that orchestrate the innate and adaptive immune systems to induce immunity. DCs are significant in maintaining immune tolerance towards self-antigens, organ transplantation and allergic responses. DCs are powerful adjuvants for eliciting T-cell immunity and are therefore considered primary targets for inducing immune responses in the prevention and treatment of infectious diseases and cancer. DCs have been increasingly applied in the immunotherapy of cancer worldwide during the last decade; however, a number of the highly specialized biological characteristics of DCs remain to be elucidated. Previous studies of human DCs have been constrained by certain difficulties, therefore the majority of studies have been carried out using in vitro model systems. Suitable cell lines with dendritic-like properties may provide valuable tools for the study of DC physiology and pathology. In the current review, various human DC line differentiation models are discussed. Certain cell lines provide valuable tools for studying the specific aspects of DC biology, despite variations in cell biological and immunological features when compared with primary DCs.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.