Evidence map›Paper›PMID 23226717›Full record

ArticleAddictive disorders & their treatment2012

The efficacy of escalating and fixed contingency management reinforcement on illicit drug use in opioid-dependent pregnant women.

Melissa L Hutchinson, Margaret S Chisolm, Michelle Tuten, Jeannie-Marie S Leoutsakos, Hendrée E Jones

Registry-linked trialAbstract read
In one paragraph

Article in Addictive disorders & their treatment, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04927143 (Encouraging Abstinence Behavior in a Drug Epidemic), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04927143 narecruitingnot on this mapstarted 2021, after this paper: background citation

Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives

TypeinterventionalSponsorWake Forest University Health SciencesRan2021 to 2026Enrolled600ConditionsOpioid-use Disorder, Cocaine Use Disorder, Opioid Use, Cocaine UseArmsApp-Based Contingency Management, Sham Control
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Contingency management interventions for tobacco and other substance use disorders in pregnancy.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2017
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Melissa L HutchinsonThe Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Margaret S Chisolm
Michelle Tuten
Jeannie-Marie S Leoutsakos
Hendrée E Jones
Johns Hopkins Medicine · USRTI International · USJohns Hopkins University · US

Funding

Tobacco Use in Opioid Agonist treated Pregnant WomenR01DA012403 · NIDA · JOHNS HOPKINS UNIVERSITY · PI JONES, HENDREE E · 1999 to 2008
$3.2M
Operant Responding in Opioid-Deficient MiceR21DA014203 · NIDA · OREGON HEALTH AND SCIENCE UNIVERSITY · PI LOW, MALCOLM JAMES · 2002 to 2004
$477k
NIDA NIH HHS R01 DA012403NIDA NIH HHS R21 DA014203
6 · The paper itself

Abstract

objectivesContingency management (CM), long known to be efficacious in the treatment of substance-dependent men and women, has also been found to be efficacious for substance-dependent pregnant women. However, the specific CM reinforcement parameters in the special population of opioid-dependent pregnant women have been less fully and systematically studied. The Drug Abuse Incentive Systems (DAISY) study, a randomized controlled trial (RCT) of opioid-dependent pregnant patients, found that escalating reinforcement was not superior to a fixed reinforcement CM schedule after a 13-week intervention. To further examine CM's reinforcement parameters in this population, this study aims to test the hypothesis that there is an early treatment response showing an escalating reinforcement schedule to be significantly more efficacious than a fixed schedule after 5 weeks of intervention in opioid-dependent pregnant patients.

methodsNine measures of opioid and cocaine abstinence among fixed and escalating CM schedule participants in the DAISY RCT (N=90) were compared over the initial 5 weeks of the intervention.

resultsNo statistically significant difference in the opioid and cocaine abstinence measures was found between escalating and fixed conditions after 5 weeks (14 opportunities for each participant to leave a urine sample). The mean (SD) number of drug negative urine samples was 8.1 (4.5) and 7.4 (4.3), for escalating and fixed groups, respectively (p=0.46).

conclusionsThese results further the scientific knowledge regarding CM treatment in opioid-dependent pregnant women by supporting the finding that the escalating and fixed CM schedules produce similar amounts of drug negatives urine samples early in treatment.

Identifiers

PMID23226717
PMCPMC3513290
OpenAlexW2041549511

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.