ArticleIndian journal of endocrinology and metabolism2012
Polycystic ovary syndrome: Is obesity a sine qua non? A clinical, hormonal, and metabolic assessment in relation to body mass index.
Article in Indian journal of endocrinology and metabolism, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Comparison of Clinical, Metabolic, and Hormonal Profiles in Obese Versus Lean Women With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.Endocrinology, diabetes & metabolism · 2026Pooled it
- Analyzing and evaluating the metabolic and endocrine characteristics between lean and obese patients with polycystic ovary syndrome: a systemic review and meta-analysis.Frontiers in endocrinology · 2025Pooled it
- Dysregulation of Endothelial cell markers in polycystic ovary syndrome.Scientific reports · 2026Article
- Assessment of Sonographic Ovarian Volume as an Potential Predictor of Polycystic Ovarian Syndrome (PCOS): A Hospital-Based Cross-Sectional StudyEndocrine, metabolic & immune disorders drug targets · 2026Article
- Role of Granulosa Cell Dysfunction in Women Infertility Associated with Polycystic Ovary Syndrome and Obesity.Biomolecules · 2025Review
- Does a Healthy Weight Body Mass Index at Onset of Idiopathic Intracranial Hypertension Change the Outcomes? A United Kingdom Prospective Cohort Study.Neuro-ophthalmology (Aeolus Press) · 2024Article
- Higher Cumulative Live Birth Rate but Also Higher Late Miscarriage Risk in Non-Obese Women with Polycystic Ovary Syndrome Undergoing the First IVF/ICSI Cycle.International journal of women's health · 2024Article
- Investigation of body mass index, insulin resistance and diabetes in patients with hirsutism.Postepy dermatologii i alergologii · 2021Article
- Article
- Cutaneous manifestation of polycystic ovary syndrome.Dermatology reports · 2021Article
- Meta-analysis of gene expression profiles of lean and obese PCOS to identify differentially regulated pathways and risk of comorbidities.Computational and structural biotechnology journal · 2020Article
- Lifestyle management of polycystic ovary syndrome: a single-center study in Bosnia and Herzegovina.AIMS public health · 2020Article
- Relationship of subclinical hypothyroidism and obesity in polycystic ovarian syndrome patients.Journal of family medicine and primary care · 2020Article
- Lean polycystic ovary syndrome (PCOS): an evidence-based practical approach.Journal of diabetes and metabolic disorders · 2018Article
- Grading of hirsutism based on the Ferriman-Gallwey scoring system in Kosovar women.Postepy dermatologii i alergologii · 2018Article
- Primary amenorrhoea and clitoromegaly in a nulliparous woman: successful medical and surgical management.BMJ case reports · 2018Article
- Endocrine and Metabolic Profile of Different Phenotypes of Polycystic Ovarian Syndrome.Journal of obstetrics and gynaecology of India · 2016Article
- Acne in hirsute women.Postepy dermatologii i alergologii · 2014Article
- Mixed form of hirsutism in an adolescent female and laser therapy.Iranian Red Crescent medical journal · 2014Article
- Cutaneous Manifestations of Polycystic Ovary Syndrome: A Cross-Sectional Clinical Study.Indian dermatology online journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the proportion of polycystic ovarian syndrome (PCOS) patients who have normal body mass index (BMI) and to compare the clinical, hormonal, and metabolic profile between lean and overweight patients of PCOS. MATERIALS AND
methodsOne hundred consecutive infertile women with PCOS were studied and divided into lean (BMI between 18.5 and 23) and overweight (BMI ≥ 23). Metabolic and hormonal profile (serum FSH, LH, testosterone, prolactin, TSH on days 2-3 of menstrual cycle; serum progesterone premenstrually; serum insulin-fasting and 2 hours postglucose, glucose tolerance test, and fasting serum lipid profile) was performed along with pelvic sonogropahy; and clinical features, viz. waist hip ratio, hirsutism, acne, acanthosis nigricans, and clitoromegaly were recorded.
results42% of the PCOS subjects had normal BMI. Average age, hirsutism (80.9% vs. 89.7%), irregular cycles (92.8% vs. 96.6%), acne (9.5% vs. 15.5%), clitoromegaly (2.3% vs. 3.4%), endometrial thickness >4 mm (9.5% vs. 15.5%), and hormonal profile were similar in the lean and overweight PCOS groups. Family history of diabetes (9.5% vs. 24.1%), abnormal glucose tolerance test (GTT) (4.7% vs. 10.3%), deranged lipid profile (14.2% vs. 31%), and 2-hour postprandial insulin levels were higher in the overweight PCOS (P < 0.05). Insulin resistance was observed in 83.3% of lean PCOS but was still lower than 93.1% seen in overweight PCOS (P < 0.05).
conclusion42% of the PCOS had normal BMI, but clinical and hormonal profile was similar to PCOS patients with elevated BMI (overweight/obese). However, insulin resistance is observed in 83.3% of lean PCOS. Family history of diabetes, impaired GTT, deranged lipid profile, and insulin resistance were more prevalent in overweight PCOS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.