Evidence map›Paper›PMID 23225813›Full record

ArticleYonsei medical journal2013

Prevalence and risk factors of esophageal candidiasis in healthy individuals: a single center experience in Korea.

Jae Hyeuk Choi, Chang Geun Lee, Yun Jeong Lim, Hyoun Woo Kang, Chi Yeon Lim, Jong-Sun Choi

Open access · goldAbstract read
In one paragraph

Article in Yonsei medical journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Article
  5. Infective Esophagitis.The Korean journal of helicobacter and upper gastrointestinal research · 2025
    Review
  6. Article
  7. [Fungal Infection in Upper Gastrointestinal Tract].The Korean journal of helicobacter and upper gastrointestinal research · 2024
    Review
  8. Article
  9. Article
  10. Prevalence and risk factors forWorld journal of clinical cases · 2022
    Article
  11. Article
  12. Article
  13. Nausea and vomiting caused by candida esophagitis in an elderly frail patient.JGH open : an open access journal of gastroenterology and hepatology · 2022
    Article
  14. Chronic fibrosing esophagitis with diffuse esophageal intramural pseudo-diverticulosis.JGH open : an open access journal of gastroenterology and hepatology · 2022
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Gastroenterology and hepatology from bed to bench · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jae Hyeuk ChoiDepartments of 1Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Korea. limyj@dongguk.ac.kr
Chang Geun Lee
Yun Jeong Lim
Hyoun Woo Kang
Chi Yeon Lim
Jong-Sun Choi
Dongguk University · KRDongguk University Ilsan Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEsophageal candidiasis (EC) is the most frequent opportunistic fungal infection in immunocompromised host. However, we have found EC in healthy individuals through esophagogastroduodenoscopy (EGD). The aim of this study was to determine the prevalence and risk factors for EC in healthy individuals. MATERIALS AND

methodsWe retrospectively reviewed the medical records of 281 patients who had been incidentally diagnosed with EC. We also conducted age and sex matched case control study to identify the risk factor for EC.

resultsThe prevalence of EC was 0.32% (281/88125). The most common coexisting EGD finding was reflux esophagitis (49/281, 17.4%). An antifungal agent was prescribed in about half of EC, 139 cases (49.5%). Follow-up EGD was undertaken in 83 cases (29.5%) and 20 cases of candidiasis was persistently found. Case control study revealed EC were more often found in user of antibiotics (p=0.015), corticosteroids (p=0.002) and herb medication (p=0.006) as well as heavy drinking (p<0.001).

conclusionThe prevalence of EC was 0.32% (281/88125) in Korea. Use of antibiotics, corticosteroids and herb as well as heavy drinking were significant risk factors for EC in healthy individuals.

Indexed as

Adrenal Cortex HormonesAdultAgedAlcohol DrinkingAnti-Bacterial AgentsAntifungal AgentsCandidiasisCase-Control StudiesEsophageal DiseasesEsophagitis, PepticFemaleHumansImmunocompromised HostMaleMiddle AgedPlant PreparationsAdrenal Cortex HormonesAnti-Bacterial AgentsAntifungal AgentsPlant Preparations

Identifiers

PMID23225813
PMCPMC3521253
OpenAlexW2120892511

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.