Evidence map›Paper›PMID 23225074›Full record

ArticleInternational journal of computer assisted radiology and surgery2013

Calibration of cone beam CT using relative attenuation ratio for quantitative assessment of bone density: a small animal study.

Yifei Liu, Tobias Bäuerle, Leyun Pan, Antonia Dimitrakopoulou-Strauss, Ludwig G Strauss, Christian Heiss, Reinhard Schnettler, Wolfhard Semmler, Liji Cao

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Article in International journal of computer assisted radiology and surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

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0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  13. Automated implant segmentation in cone-beam CT using edge detection and particle counting.International journal of computer assisted radiology and surgery · 2014
    Article
  14. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yifei LiuDepartment of Medical Physics in Radiology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 , Heidelberg, Germany.
Tobias Bäuerle
Leyun Pan
Antonia Dimitrakopoulou-Strauss
Ludwig G Strauss
Christian Heiss
Reinhard Schnettler
Wolfhard Semmler
Liji Cao

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCone beam computed tomography (CBCT) has the disadvantage of providing non-quantitative results for bone density determination. The aim of this study is to calibrate CBCT results by using an internal reference (such as muscle) for quantitatively assessing bone density.

methodsWe developed a new method using the relative attenuation ratio between two nearby materials (such as bone and muscle) for systemic error correction in CBCT that depends on the relative object position in the image volume. Phantom calibration was performed to calculate the acquired attenuation ratio in Hounsfield units (HU), comparable to the results from clinical multislice spiral computed tomography (MSCT). In addition, a small animal study with an osteoporotic rat model was evaluated to show the feasibility of this presented method to quantitatively assess bone density using a CBCT system.

resultsThe phantom study results showed that the calibration process successfully corrected the systemic inaccuracy from CBCT, and the calibrated HU values agreed with the values measured from MSCT. In the small animal study, the quantitative bone densities assessed from the calibrated CBCT results were consistent with the results from MSCT data.

conclusionA practical method to quantitatively estimate attenuation (HU) values for bone tissues from CBCT scans that are comparable to MSCT scans is proposed. The method may improve the quantification ability of CBCT scanning without any additional hardware requirements.

Indexed as

Bone DensityModels, TheoreticalPhantoms, ImagingAnimalsCalibrationCone-Beam Computed TomographyDisease Models, AnimalOsteoporosisRatsReproducibility of ResultsSacrum

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.