Evidence map›Paper›PMID 23224513›Full record

ArticleJournal of autism and developmental disorders2013

Empirically based phenotypic profiles of children with pervasive developmental disorders: interpretation in the light of the DSM-5.

Kirstin Greaves-Lord, Mart L J M Eussen, Frank C Verhulst, Ruud B Minderaa, William Mandy, James J Hudziak, Mark Peter Steenhuis, Pieter F de Nijs, Catharina A Hartman

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Evaluation of Erythropoietin and Erythropoietin Receptor Levels in Children with Autistic Spectrum Disorder: Cross-sectional Study.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025
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  11. Classifying Autism Spectrum Disorders by ADI-R: Subtypes or Severity Gradient?Journal of autism and developmental disorders · 2016
    Article
  12. Article
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  16. Article
  17. Autism assessment tools in the transition from DSM-IV to DSM-5.European child & adolescent psychiatry · 2013
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kirstin Greaves-LordDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus Medical Center Rotterdam/Sophia Children's Hospital, Dr. Molewaterplein 60, 3015 GJ, Rotterdam, The Netherlands. k.greaves-lord@erasmusmc.nl
Mart L J M Eussen
Frank C Verhulst
Ruud B Minderaa
William Mandy
James J Hudziak
Mark Peter Steenhuis
Pieter F de Nijs
Catharina A Hartman

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to contribute to the Diagnostic and Statistical Manual (DSM) debates on the conceptualization of autism by investigating (1) whether empirically based distinct phenotypic profiles could be distinguished within a sample of mainly cognitively able children with pervasive developmental disorder (PDD), and (2) how profiles related to diagnoses and co-occurring behavioral and emotional problems. Six classes with distinct profiles were discerned. Three classes showed profiles not completely in line with the proposed DSM-5 conceptualization of autism. These classes included relatively many cognitively able individuals with PDD-not otherwise specified. However, profiles seemed to suit other diagnostic categories, such as social communication disorder. These alternative diagnoses could retain eligibility for services, and might adequately fit more specifically targeted interventions.

Indexed as

Diagnostic and Statistical Manual of Mental DisordersPhenotypeAdolescentAsperger SyndromeChildChild Development Disorders, PervasiveComorbidityFemaleHumansIntellectual DisabilityMalePsychiatric Status Rating Scales

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.