ReviewMammalian genome : official journal of the International Mammalian Genome Society2013
Deconstructing Mus gemischus: advances in understanding ancestry, structure, and variation in the genome of the laboratory mouse.
Review in Mammalian genome : official journal of the International Mammalian Genome Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 61 citations in OpenAlex.
- Phenogenomic resources immortalized in a panel of wild-derived strains of five species of house mice.Scientific reports · 2025Article
- Evaluation of Biocomposite Cements for Bone Defect Repair in Rat Models.Life (Basel, Switzerland) · 2024Article
- The Potential of Composite Cements for Wound Healing in Rats.Bioengineering (Basel, Switzerland) · 2024Article
- Assessing Biocompatibility of Composite Cements by Peri/Intramuscular and Subcutaneous Implantation in Rats.Biomedicines · 2024Article
- Across two continents: The genomic basis of environmental adaptation in house mice (Mus musculus domesticus) from the Americas.PLoS genetics · 2024Article
- The Expansion of House Mouse Major Urinary Protein Genes Likely Did Not Facilitate Commensalism with Humans.Genes · 2023Article
- Across two continents: the genomic basis of environmental adaptation in house mice (bioRxiv : the preprint server for biology · 2023Article
- The demographic history of house mice (Mus musculus domesticus) in eastern North America.G3 (Bethesda, Md.) · 2023Article
- Population structure and inbreeding in wild house mice (Mus musculus) at different geographic scales.Heredity · 2022Article
- Insights into Mus musculus Population Structure across Eurasia Revealed by Whole-Genome Analysis.Genome biology and evolution · 2022Article
- Regulation of Sexually Dimorphic Expression of Major Urinary Proteins.Frontiers in physiology · 2022Review
- New Perspective on the Geographic Distribution and Evolution of Lymphocytic Choriomeningitis Virus, Central Europe.Emerging infectious diseases · 2021Article
- The genomics of rapid climatic adaptation and parallel evolution in North American house mice.PLoS genetics · 2021Article
- The Impact of Composites with Silicate-Based Glasses and Gold Nanoparticles on Skin Wound Regeneration.Molecules (Basel, Switzerland) · 2021Article
- Article
- Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research.Genetics · 2020Article
- Interactions between host genetics and gut microbiota determine susceptibility to CNS autoimmunity.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Further resolution of the house mouse (Mus musculus) phylogeny by integration over isolation-with-migration histories.BMC evolutionary biology · 2020Article
- Article
- Whole exome sequencing of wild-derived inbred strains of mice improves power to link phenotype and genotype.Mammalian genome : official journal of the International Mammalian Genome Society · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The laboratory mouse is an artificial construct with a complex relationship to its natural ancestors. In 2002, the mouse became the first mammalian model organism with a reference genome. Importantly, the mouse genome sequence was assembled from data on a single inbred laboratory strain, C57BL/6. Several large-scale genetic variant discovery efforts have been conducted, resulting in a catalog of tens of millions of SNPs and structural variants. High-density genotyping arrays covering a subset of those variants have been used to produce hundreds of millions of genotypes in laboratory stocks and a small number of wild mice. These landmark resources now enable us to determine relationships among laboratory mice, assign local ancestry at fine scale, resolve important controversies, and identify a new set of challenges-most importantly, the troubling scarcity of genetic data on the very natural populations from which the laboratory mouse was derived. Our aim with this review is to provide the reader with an historical context for the mouse as a model organism and to explain how practical decisions made in the past have influenced both the architecture of the laboratory mouse genome and the design and execution of current large-scale resources. We also provide examples on how the accomplishments of the past decade can be used by researchers to streamline the use of mice in their experiments and correctly interpret results. Finally, we propose future steps that will enable the mouse community to extend its successes in the decade to come.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.