ArticleGenetics2013
A connected set of genes associated with programmed cell death implicated in controlling the hypersensitive response in maize.
Article in Genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Determination of genomic regions associated with early storage root formation and bulking in cassava.Frontiers in plant science · 2024Article
- Qmatey: an automated pipeline for fast exact matching-based alignment and strain-level taxonomic binning and profiling of metagenomes.Briefings in bioinformatics · 2023Article
- The maize ZmVPS23-like protein relocates the nucleotide-binding leucine-rich repeat protein Rp1-D21 to endosomes and suppresses the defense response.The Plant cell · 2023Article
- Elucidating the patterns of pleiotropy and its biological relevance in maize.PLoS genetics · 2023Article
- Brown midrib mutant and genome-wide association analysis uncover lignin genes for disease resistance in maize.The plant genome · 2023Article
- The maize ZmMIEL1 E3 ligase and ZmMYB83 transcription factor proteins interact and regulate the hypersensitive defence response.Molecular plant pathology · 2021Article
- Maize nicotinate N-methyltransferase interacts with the NLR protein Rp1-D21 and modulates the hypersensitive response.Molecular plant pathology · 2021Article
- Article
- Use of virus-induced gene silencing to characterize genes involved in modulating hypersensitive cell death in maize.Molecular plant pathology · 2020Article
- Maize ZmFNSI Homologs Interact with an NLR Protein to Modulate Hypersensitive Response.International journal of molecular sciences · 2020Article
- The Past, Present, and Future of Maize Improvement: Domestication, Genomics, and Functional Genomic Routes toward Crop Enhancement.Plant communications · 2020Review
- Genome-wide association study identified candidate genes controlling continuous storage root formation and bulking in hexaploid sweetpotato.BMC plant biology · 2020Article
- Genome-wide association analysis for maize stem Cell Wall-bound Hydroxycinnamates.BMC plant biology · 2019Article
- The plant hypersensitive response: concepts, control and consequences.Molecular plant pathology · 2019Review
- A maize polygalacturonase functions as a suppressor of programmed cell death in plants.BMC plant biology · 2019Article
- A Genome Wide Association Study Reveals Markers and Genes Associated with Resistance toG3 (Bethesda, Md.) · 2019Article
- AG3 (Bethesda, Md.) · 2019Article
- Identification of a locus in maize controlling response to a host-selective toxin derived from Cochliobolus heterostrophus, causal agent of southern leaf blight.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
- Teosinte in Europe - Searching for the Origin of a Novel Weed.Scientific reports · 2017Article
- The Maize MID-COMPLEMENTING ACTIVITY Homolog CELL NUMBER REGULATOR13/NARROW ODD DWARF Coordinates Organ Growth and Tissue Patterning.The Plant cell · 2017Article
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Authors and funding
18 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Rp1-D21 is a maize auto-active resistance gene conferring a spontaneous hypersensitive response (HR) of variable severity depending on genetic background. We report an association mapping strategy based on the Mutant Assisted Gene Identification and Characterization approach to identify naturally occurring allelic variants associated with phenotypic variation in HR. Each member of a collection of 231 diverse inbred lines of maize constituting a high-resolution association mapping panel were crossed to a parental stock heterozygous for Rp1-D21, and the segregating F(1) generation testcrosses were evaluated for phenotypes associated with lesion severity for 2 years at two locations. A genome-wide scan for associations with HR was conducted with 47,445 SNPs using a linear mixed model that controlled for spurious associations due to population structure. Since the ability to identify candidate genes and the resolution of association mapping are highly influenced by linkage disequilibrium (LD), we examined the extent of genome-wide LD. On average, marker pairs separated by >10 kbp had an r(2) value of <0.1. Genomic regions surrounding SNPs significantly associated with HR traits were locally saturated with additional SNP markers to establish local LD structure and precisely identify candidate genes. Six significantly associated SNPs at five loci were detected. At each locus, the associated SNP was located within or immediately adjacent to candidate causative genes predicted to play significant roles in the control of programmed cell death and especially in ubiquitin pathway-related processes.
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