Evidence map›Paper›PMID 23222207›Full record

ArticleInternational journal of environmental research and public health2012

Association between hypertension and chronic arsenic exposure in drinking water: a cross-sectional study in Bangladesh.

Mohammad Rafiqul Islam, Ismail Khan, John Attia, Sheikh Mohammad Nazmul Hassan, Mark McEvoy, Catherine D'Este, Syed Azim, Ayesha Akhter, Shahnaz Akter, Sheikh Mohammad Shahidullah and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Chronic arsenic exposure and cardiometabolic biomarkers in adolescents in the MINIMat longitudinal study.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Update of the risk assessment of inorganic arsenic in food.EFSA journal. European Food Safety Authority · 2024
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Health effects among a cohort exposed to low-level arsenic in a geothermal area of Tuscany, Italy.International archives of occupational and environmental health · 2018
    Article
  19. Effects of arsenic toxicity beyond epigenetic modifications.Environmental geochemistry and health · 2018
    Review
  20. Assessment of heart rate response to exercise and recovery during treadmill testing in arsenic-exposed workers.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Mohammad Rafiqul IslamCentre for Clinical Epidemiology & Biostatistics, The University of Newcastle, New Lambton Heights, NSW, Australia. mdrafiqul.islam@newcastle.edu.au
Ismail Khan
John Attia
Sheikh Mohammad Nazmul Hassan
Mark McEvoy
Catherine D'Este
Syed Azim
Ayesha Akhter
Shahnaz Akter
Sheikh Mohammad Shahidullah
Abul Hasnat Milton
University of Newcastle Australia · AUAtish Dipankar University of Science and Technology · BDDhaka Medical College and Hospital · BDInstitute of Child and Mother Health · BDUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic arsenic exposure and its association with hypertension in adults are inconclusive and this cross-sectional study investigated the association. The study was conducted between January and July 2009 among 1,004 participants from 1,682 eligible women and men aged ≥30 years living in rural Bangladesh who had continuously consumed arsenic-contaminated drinking water for at least 6 months. Hypertension was defined as systolic blood pressure ≥140 mmHg (systolic hypertension) and diastolic blood pressure ≥90 mmHg (diastolic hypertension). Pulse pressure was calculated by deducting diastolic from systolic pressure and considered to be increased when the difference was ≥55 mmHg. The prevalence of hypertension was 6.6% (95% CI: 5.1-8.3%). After adjustment for other factors, no excess risk of hypertension was observed for arsenic exposure >50 μg/L or to that of arsenic exposure as quartiles or as duration. Arsenic concentration as quartiles and >50 μg/L did show a strong relationship with increased pulse pressure (adjusted OR: 3.54, 95% CI: 1.46-8.57), as did arsenic exposure for ≥10 years (adjusted OR: 5.25, 95% CI: 1.41-19.51). Arsenic as quartiles showed a dose response relationship with increased pulse pressure. Our study suggests an association between higher drinking water arsenic or duration and pulse pressure, but not hypertension.

Indexed as

Environmental ExposureAdultArsenicBangladeshBlood PressureCross-Sectional StudiesDose-Response Relationship, DrugDrinking WaterFemaleHumansHypertensionLogistic ModelsMaleMiddle AgedPrevalenceRiskArsenicDrinking WaterWater Pollutants, Chemical

Identifiers

PMID23222207
PMCPMC3546776
OpenAlexW2146880039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.