ArticleNucleic acids research2013
UV damage endonuclease employs a novel dual-dinucleotide flipping mechanism to recognize different DNA lesions.
Article in Nucleic acids research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Cultivation and molecular profiling reveal ammonia-oxidizing archaea as skin commensals.The ISME journal · 2026Article
- Environmental distribution, physiology and genomic adaptations of arctic ammonia-oxidizing archaea.Frontiers in microbiology · 2026Article
- Common themes in architecture and interactions of prokaryotic PolB2 and Pol V mutasomes inferred fromComputational and structural biotechnology journal · 2025Article
- An Ancient Respiratory System in the Widespread Sedimentary Archaea Thermoprofundales.Molecular biology and evolution · 2022Article
- The interplay of supercoiling and thymine dimers in DNA.Nucleic acids research · 2022Article
- Review
- Comparative genomics reveals insights into cyanobacterial evolution and habitat adaptation.The ISME journal · 2021Article
- AP-endonuclease 1 sculpts DNA through an anchoring tyrosine residue on the DNA intercalating loop.Nucleic acids research · 2020Article
- Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Role of Base Excision Repair Pathway in the Processing of Complex DNA Damage Generated by Oxidative Stress and Anticancer Drugs.Frontiers in cell and developmental biology · 2020Review
- Over-Expression of UV-Damage DNA Repair Genes and Ribonucleic Acid Persistence Contribute to the Resilience of Dried Biofilms of the Desert CyanobacetriumFrontiers in microbiology · 2019Article
- Article
- Modulation of UVB-induced Carcinogenesis by Activation of Alternative DNA Repair Pathways.Scientific reports · 2018Article
- Both DNA global deformation and repair enzyme contacts mediate flipping of thymine dimer damage.Scientific reports · 2017Article
- The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once.DNA repair · 2014Review
- CRISPR-mediated targeted mRNA degradation in the archaeon Sulfolobus solfataricus.Nucleic acids research · 2014Article
- Attenuated NER expressions of XPF and XPC associated with smoking are involved in the recurrence of bladder cancer.PloS one · 2014Article
- Base pair opening in a deoxynucleotide duplex containing a cis-syn thymine cyclobutane dimer lesion.Biochemistry · 2013Article
- The Uve1 endonuclease is regulated by the white collar complex to protect cryptococcus neoformans from UV damage.PLoS genetics · 2013Article
- Structure-based function prediction of uncharacterized protein using binding sites comparison.PLoS computational biology · 2013Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Repairing damaged DNA is essential for an organism's survival. UV damage endonuclease (UVDE) is a DNA-repair enzyme that can recognize and incise different types of damaged DNA. We present the structure of Sulfolobus acidocaldarius UVDE on its own and in a pre-catalytic complex with UV-damaged DNA containing a 6-4 photoproduct showing a novel 'dual dinucleotide flip' mechanism for recognition of damaged dipyrimidines: the two purines opposite to the damaged pyrimidine bases are flipped into a dipurine-specific pocket, while the damaged bases are also flipped into another cleft.
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